Mice Deleted for Fatty Acid Transport Protein 5 Have Defective Bile Acid Conjugation and Are Protected From Obesity

Background & Aims: Fatty Acid Transport Protein 5 (FATP5) is a liver-specific member of the FATP/Slc27 family, which has been shown to exhibit both fatty acid transport and bile acid-CoA ligase activity in vitro. Here, we investigate its role in bile acid metabolism and body weight homeostasis i...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2006-04, Vol.130 (4), p.1259-1269
Hauptverfasser:	Hubbard, Brian, Doege, Holger, Punreddy, Sandhya, Wu, Hui, Huang, Xueming, Kaushik, Virendar K., Mozell, Robin L., Byrnes, John J., Stricker–Krongrad, Alain, Chou, Chieh J., Tartaglia, Louis A., Lodish, Harvey F., Stahl, Andreas, Gimeno, Ruth E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Aging - metabolism Animals Bile Acids and Salts - metabolism Body Weight Dietary Fats - administration & dosage Dose-Response Relationship, Drug Eating Energy Metabolism Fatty Acid Transport Proteins - deficiency Gallbladder - metabolism Gene Expression Lipid Metabolism Male Mice Mice, Knockout Obesity - etiology Obesity - prevention & control
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