Targeted Deletion of FATP5 Reveals Multiple Functions in Liver Metabolism: Alterations in Hepatic Lipid Homeostasis

Background & Aims: Fatty acid transport protein 5 (FATP5/Slc27a5) has been shown to be a multifunctional protein that in vitro increases both uptake of fluorescently labeled long-chain fatty acid (LCFA) analogues and bile acid/coenzyme A ligase activity on overexpression. The aim of this study w...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2006-04, Vol.130 (4), p.1245-1258
Hauptverfasser:	Doege, Holger, Baillie, Rebecca A., Ortegon, Angelica M., Tsang, Bernice, Wu, Qiwei, Punreddy, Sandhya, Hirsch, David, Watson, Nicki, Gimeno, Ruth E., Stahl, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bile Acids and Salts - metabolism Cells, Cultured Dietary Fats - pharmacokinetics Fasting Fatty Acid Transport Proteins - deficiency Fatty Acid Transport Proteins - metabolism Fatty Acid Transport Proteins - physiology Fatty Acids - biosynthesis Fatty Acids - metabolism Hepatocytes - metabolism Homeostasis - physiology Ketone Bodies - metabolism Lipid Metabolism - physiology Liver - metabolism Mice Mice, Knockout Tissue Distribution Triglycerides - metabolism
Online-Zugang:	Volltext
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