Transforming Growth Factor Beta‐Induced Connective Tissue Growth Factor and Chronic Allograft Rejection

Late loss of allograft function is primarily attributed to chronic rejection (CR). There are no effective treatments for CR and the underlying cause of the disease is unknown. This study compared events that occurred within cardiac allografts placed in mice that received either anti‐CD4 therapy and...

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Veröffentlicht in:	American journal of transplantation 2006-05, Vol.6 (5p1), p.959-966
Hauptverfasser:	Csencsits, K., Wood, S. C., Lu, G., Faust, S. M., Brigstock, D., Eichwald, E. J., Orosz, C. G., Bishop, D. K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences CD40 Ligand - immunology Chronic rejection Connective Tissue Growth Factor Female fibrosis Graft Rejection - pathology Heart Transplantation - immunology Heart Transplantation - pathology Immediate-Early Proteins - genetics Immediate-Early Proteins - immunology Immediate-Early Proteins - physiology Immunohistochemistry Intercellular Signaling Peptides and Proteins - genetics Intercellular Signaling Peptides and Proteins - immunology Intercellular Signaling Peptides and Proteins - physiology Male Medical sciences Mice Mice, Inbred BALB C Mice, Inbred C57BL Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Transfection transforming growth factor beta Transforming Growth Factor beta - immunology Transforming Growth Factor beta - physiology Transplantation, Homologous Transplantation, Isogeneic
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