High-throughput loss-of-heterozygosity study of chromosome 3p in lung cancer using single-nucleotide polymorphism markers

Loss of DNA copy number at the short arm of chromosome 3 is one of the most common genetic changes in human lung cancer, suggesting the existence of one or more tumor suppressor genes (TSG) at 3p. To identify most frequently deleted regions and candidate TSGs within these regions, a recently develop...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2006-04, Vol.66 (8), p.4133-4138
Hauptverfasser:	TAI, Amy L. S, MAK, William, MINYUE ZHANG, SHAM, Pak C, GUAN, Xin-Yuan, NG, Phoebe K. M, CHUA, Daniel T. T, NG, Mandy Y. M, LI FU, CHU, Kevin K. W, YAN FANG, YOU QIANG SONG, MUHAN CHEN
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences Carcinoma, Non-Small-Cell Lung - genetics Chromosomes, Human, Pair 3 - genetics Genes, Tumor Suppressor Genotype Humans Loss of Heterozygosity Lung Neoplasms - genetics Medical sciences Nucleic Acid Hybridization Pharmacology. Drug treatments Pneumology Polymorphism, Single Nucleotide Reproducibility of Results Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Tumors Tumors of the respiratory system and mediastinum
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