Uptake of triacylglycerol-rich lipoproteins of differing triacylglycerol molecular species and unsaponifiable content by liver cells

The fatty acid composition of dietary oils can modulate the incorporation of triacylglycerol-rich lipoproteins (TRL) into hepatocytes, thus affecting the atherogenicity of these particles. However, nothing is known about the effect of the unsaponifiable fraction of the oils. In the present study, we...

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Veröffentlicht in:	British journal of nutrition 2006-05, Vol.95 (5), p.889-897
Hauptverfasser:	Perona, Javier S., Avella, Michael, Botham, Kathleen M., Ruiz-Gutierrez, Valentina
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult animal models Animals atherogenesis Biological and medical sciences Cells, Cultured chemical structure Diet dietary fat Dietary Fats, Unsaturated - pharmacokinetics Dietary Fats, Unsaturated - pharmacology fatty acid composition Fatty acids Fatty Acids - analysis Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Gene Expression Regulation - drug effects Glycerol hepatocytes Hepatocytes - metabolism Humans Lipoproteins Lipoproteins - chemistry Lipoproteins - pharmacokinetics Liver Low Density Lipoprotein Receptor-Related Protein-1 - biosynthesis Low Density Lipoprotein Receptor-Related Protein-1 - genetics Low density lipoprotein receptors Male Meals Microscopy, Confocal Nutrition research Olive Oil Plant Oils - chemistry Plant Oils - pharmacology Postprandial Period - physiology protein synthesis Proteins Rats receptors RNA, Messenger - genetics saponification Sunflower Oil transcription (genetics) Triacylglycerol Triacylglycerol-rich lipoprotein triacylglycerols Triglycerides - analysis Triglycerides - pharmacokinetics unsaponifiable content Uptake uptake mechanisms Vertebrates: anatomy and physiology, studies on body, several organs or systems
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