The contribution of nitric oxide and vasodilatory prostanoids to bradykinin-mediated vasodilation in Type 1 diabetes

Aims To investigate the effect of bradykinin on endothelial tone in normoalbuminuric Type 1 diabetic patients and specifically whether any changes are mediated through nitric oxide or prostaglandins. Methods Forearm blood flow was measured using venous occlusion plethysmography at baseline and aft...

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Veröffentlicht in:	Diabetic medicine 2005-06, Vol.22 (6), p.697-702
Hauptverfasser:	Wotherspoon, F., Browne, D. L., Meeking, D. R., Allard, S. E., Munday, L. J., Shaw, K. M., Cummings, M. H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences bradykinin Bradykinin - administration & dosage Bradykinin - pharmacology Diabetes Mellitus, Type 1 - physiopathology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies endothelial function Endothelium, Vascular - drug effects Female Forearm - blood supply Humans Male Medical sciences Middle Aged nitric oxide Nitric Oxide - physiology prostaglandins Prostaglandins - physiology Regional Blood Flow - drug effects Type 1 diabetes Vasodilation - drug effects Vasodilator Agents - pharmacology
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