Both Selenoproteins and Low Molecular Weight Selenocompounds Reduce Colon Cancer Risk in Mice with Genetically Impaired Selenoprotein Expression

Selenium has cancer protective effects in a variety of experimental systems. Currently, it is not known whether selenoproteins or low molecular weight selenocompounds are responsible for this activity. To evaluate the contribution of selenoproteins to the cancer protective effects of selenium, we us...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of nutrition 2006-05, Vol.136 (5), p.1311-1317
Hauptverfasser:	Irons, Robert, Carlson, Bradley A, Hatfield, Dolph L, Davis, Cindy D
Format:	Artikel
Sprache:	eng
Schlagworte:	animal models Animals Anticarcinogenic Agents - therapeutic use Biological and medical sciences chemoprevention colon Colon - metabolism Colonic Neoplasms - genetics Colonic Neoplasms - prevention & control colorectal neoplasms cysteine Diet dietary minerals disease resistance enzyme activity Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology gene expression genotype glutathione peroxidase homeostasis human diseases human nutrition intestinal crypts liver Liver - metabolism Mice Mice, Inbred Strains Mice, Transgenic mutants protein synthesis RNA, Transfer - genetics selenites selenium Selenium - administration & dosage Selenium - analysis Selenium - therapeutic use seleno amino acids Selenoproteins - deficiency Selenoproteins - genetics Selenoproteins - therapeutic use thioredoxin-disulfide reductase transgenic animals transporters Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!