Strict Pairing of var Promoters and Introns Is Required for var Gene Silencing in the Malaria Parasite Plasmodium falciparum

The human malaria parasite, Plasmodium falciparum, maintains a persistent infection altering the proteins expressed on the surface of the infected red blood cells, thus avoiding the host immune response. The primary surface antigen, a protein called PfEMP1, is encoded by a multicopy gene family call...

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