The effect of treatment on health-related quality of life in patients with hypertension and renal artery stenosis
The quality of life in patients with hypertension is considered to be impaired mainly by side effects of antihypertensive drug therapy. Since balloon angioplasty for renal artery stenosis has a medication-sparing effect, it may lead to an improvement in quality of life. The objective of the study is...
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Veröffentlicht in: | Journal of human hypertension 2005-06, Vol.19 (6), p.467-470 |
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description | The quality of life in patients with hypertension is considered to be impaired mainly by side effects of antihypertensive drug therapy. Since balloon angioplasty for renal artery stenosis has a medication-sparing effect, it may lead to an improvement in quality of life. The objective of the study is to compare the effect of antihypertensive drug therapy and balloon angioplasty on quality of life in patients with hypertension and renal artery stenosis. We compared the quality of life in 56 patients randomised to balloon angioplasty to that in 50 patients randomised to antihypertensive drug therapy after 3 and 12 months of follow-up. Quality of life was measured using a questionnaire on physical symptoms associated with hypertension and antihypertensive drugs, and two generic health questionnaires (MOS Survey and EuroQol instrument). After follow-up, the patients who underwent angioplasty used less antihypertensive drugs than the patients who were treated with antihypertensive drugs only (mean±s.d., 1.9±0.9
vs
2.5±1.0 drugs after 3 months,
P
=0.002). They reported similar physical complaints, however, and a similar quality of life. The results after 12 months of follow-up were the same. In conclusion, for patients with hypertension and renal artery stenosis, the decrease in antihypertensive medication after intervention is too small to lead to a detectable improvement in quality of life. |
doi_str_mv | 10.1038/sj.jhh.1001847 |
format | Article |
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vs
2.5±1.0 drugs after 3 months,
P
=0.002). They reported similar physical complaints, however, and a similar quality of life. The results after 12 months of follow-up were the same. In conclusion, for patients with hypertension and renal artery stenosis, the decrease in antihypertensive medication after intervention is too small to lead to a detectable improvement in quality of life.</description><identifier>ISSN: 0950-9240</identifier><identifier>EISSN: 1476-5527</identifier><identifier>DOI: 10.1038/sj.jhh.1001847</identifier><identifier>PMID: 15759023</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Aged ; Angioplasty ; Angioplasty, Balloon ; Antihypertensive agents ; Antihypertensive Agents - therapeutic use ; Antihypertensives ; Arterial hypertension. Arterial hypotension ; Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology. Vascular system ; Cardiovascular system ; Care and treatment ; Clinical manifestations. Epidemiology. Investigative techniques. Etiology ; Diuretics ; Drug therapy ; Epidemiology ; Female ; Follow-Up Studies ; Health Administration ; Health aspects ; Humans ; Hypertension ; Hypertension - drug therapy ; Hypertension - etiology ; Hypertension - physiopathology ; Male ; Medical sciences ; Medicine ; Medicine & Public Health ; Middle Aged ; original-article ; Patient outcomes ; Patients ; Pharmacology. Drug treatments ; Public Health ; Quality of Life ; Renal artery ; Renal artery obstruction ; Renal Artery Obstruction - complications ; Renal Artery Obstruction - physiopathology ; Renal Artery Obstruction - therapy ; Stenosis ; Stents ; Surveys and Questionnaires</subject><ispartof>Journal of human hypertension, 2005-06, Vol.19 (6), p.467-470</ispartof><rights>Springer Nature Limited 2005</rights><rights>2005 INIST-CNRS</rights><rights>COPYRIGHT 2005 Nature Publishing Group</rights><rights>Copyright Nature Publishing Group Jun 2005</rights><rights>Nature Publishing Group 2005.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c538t-8f12888ebcfc77ccb2965993a055c0af328951cdbf35cf86cae66333d91a57e93</citedby><cites>FETCH-LOGICAL-c538t-8f12888ebcfc77ccb2965993a055c0af328951cdbf35cf86cae66333d91a57e93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/sj.jhh.1001847$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/sj.jhh.1001847$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27922,27923,41486,42555,51317</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16801084$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15759023$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Krijnen, P</creatorcontrib><creatorcontrib>van Jaarsveld, B C</creatorcontrib><creatorcontrib>Hunink, M G M</creatorcontrib><creatorcontrib>Habbema, J D F</creatorcontrib><title>The effect of treatment on health-related quality of life in patients with hypertension and renal artery stenosis</title><title>Journal of human hypertension</title><addtitle>J Hum Hypertens</addtitle><addtitle>J Hum Hypertens</addtitle><description>The quality of life in patients with hypertension is considered to be impaired mainly by side effects of antihypertensive drug therapy. Since balloon angioplasty for renal artery stenosis has a medication-sparing effect, it may lead to an improvement in quality of life. The objective of the study is to compare the effect of antihypertensive drug therapy and balloon angioplasty on quality of life in patients with hypertension and renal artery stenosis. We compared the quality of life in 56 patients randomised to balloon angioplasty to that in 50 patients randomised to antihypertensive drug therapy after 3 and 12 months of follow-up. Quality of life was measured using a questionnaire on physical symptoms associated with hypertension and antihypertensive drugs, and two generic health questionnaires (MOS Survey and EuroQol instrument). After follow-up, the patients who underwent angioplasty used less antihypertensive drugs than the patients who were treated with antihypertensive drugs only (mean±s.d., 1.9±0.9
vs
2.5±1.0 drugs after 3 months,
P
=0.002). They reported similar physical complaints, however, and a similar quality of life. The results after 12 months of follow-up were the same. In conclusion, for patients with hypertension and renal artery stenosis, the decrease in antihypertensive medication after intervention is too small to lead to a detectable improvement in quality of life.</description><subject>Aged</subject><subject>Angioplasty</subject><subject>Angioplasty, Balloon</subject><subject>Antihypertensive agents</subject><subject>Antihypertensive Agents - therapeutic use</subject><subject>Antihypertensives</subject><subject>Arterial hypertension. Arterial hypotension</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular system</subject><subject>Care and treatment</subject><subject>Clinical manifestations. Epidemiology. Investigative techniques. Etiology</subject><subject>Diuretics</subject><subject>Drug therapy</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Health Administration</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Hypertension - drug therapy</subject><subject>Hypertension - etiology</subject><subject>Hypertension - physiopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>original-article</subject><subject>Patient outcomes</subject><subject>Patients</subject><subject>Pharmacology. Drug treatments</subject><subject>Public Health</subject><subject>Quality of Life</subject><subject>Renal artery</subject><subject>Renal artery obstruction</subject><subject>Renal Artery Obstruction - complications</subject><subject>Renal Artery Obstruction - physiopathology</subject><subject>Renal Artery Obstruction - therapy</subject><subject>Stenosis</subject><subject>Stents</subject><subject>Surveys and Questionnaires</subject><issn>0950-9240</issn><issn>1476-5527</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kk1vGyEQhldVq8ZJe-2tFWrU3NaBZWHhGEX9kiL1kp4RZocsFmZtYBX53xfXKzmtEnEAZp53Zhimqj4QvCSYiuu0Xq6HoZwxEW33qlqQtuM1Y033ulpgyXAtmxafVecprQtTnOJtdUZYxyRu6KLa3Q-AwFowGY0W5Qg6byCUS0ADaJ-HOoLXGXq0m7R3eX_AvLOAXEBbnV2BE3p0eUDDfgsxQ0iuiHXoUYSgPdLFFvcoFc-YXHpXvbHaJ3g_7xfV729f729_1He_vv-8vbmrDaMi18KSRggBK2NN1xmzaiRnUlKNGTNYW9oIyYjpV5YyYwU3GjinlPaSaNaBpBfV1THuNo67CVJWG5cMeK8DjFNSvBMMN6wt4OV_4HqcYqk8qYa3mNO2kaxQn1-kiJScN608hXrQHpQLdsxRm0NedUNEqQ534pBw-QxVVg8bZ8YA1hX7P4KrJ4Ljt6TRT7k0Oj0b2cQxpQhWbaPb6LhXBKvDvKi0VmVe1DwvRfBpftW02kB_wucBKcCXGdDJaG-jDsalE8cFJvhv5usjl4orPEA8tefF1B-PiqDzFOFJpUf_H8A94Hw</recordid><startdate>20050601</startdate><enddate>20050601</enddate><creator>Krijnen, P</creator><creator>van Jaarsveld, B C</creator><creator>Hunink, M G M</creator><creator>Habbema, J D F</creator><general>Nature Publishing Group UK</general><general>Nature Publishing</general><general>Nature Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20050601</creationdate><title>The effect of treatment on health-related quality of life in patients with hypertension and renal artery stenosis</title><author>Krijnen, P ; van Jaarsveld, B C ; Hunink, M G M ; Habbema, J D F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c538t-8f12888ebcfc77ccb2965993a055c0af328951cdbf35cf86cae66333d91a57e93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Aged</topic><topic>Angioplasty</topic><topic>Angioplasty, Balloon</topic><topic>Antihypertensive agents</topic><topic>Antihypertensive Agents - therapeutic use</topic><topic>Antihypertensives</topic><topic>Arterial hypertension. Arterial hypotension</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular system</topic><topic>Care and treatment</topic><topic>Clinical manifestations. Epidemiology. Investigative techniques. Etiology</topic><topic>Diuretics</topic><topic>Drug therapy</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Health Administration</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Hypertension - drug therapy</topic><topic>Hypertension - etiology</topic><topic>Hypertension - physiopathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>original-article</topic><topic>Patient outcomes</topic><topic>Patients</topic><topic>Pharmacology. Drug treatments</topic><topic>Public Health</topic><topic>Quality of Life</topic><topic>Renal artery</topic><topic>Renal artery obstruction</topic><topic>Renal Artery Obstruction - complications</topic><topic>Renal Artery Obstruction - physiopathology</topic><topic>Renal Artery Obstruction - therapy</topic><topic>Stenosis</topic><topic>Stents</topic><topic>Surveys and Questionnaires</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Krijnen, P</creatorcontrib><creatorcontrib>van Jaarsveld, B C</creatorcontrib><creatorcontrib>Hunink, M G M</creatorcontrib><creatorcontrib>Habbema, J D F</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of human hypertension</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Krijnen, P</au><au>van Jaarsveld, B C</au><au>Hunink, M G M</au><au>Habbema, J D F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of treatment on health-related quality of life in patients with hypertension and renal artery stenosis</atitle><jtitle>Journal of human hypertension</jtitle><stitle>J Hum Hypertens</stitle><addtitle>J Hum Hypertens</addtitle><date>2005-06-01</date><risdate>2005</risdate><volume>19</volume><issue>6</issue><spage>467</spage><epage>470</epage><pages>467-470</pages><issn>0950-9240</issn><eissn>1476-5527</eissn><abstract>The quality of life in patients with hypertension is considered to be impaired mainly by side effects of antihypertensive drug therapy. Since balloon angioplasty for renal artery stenosis has a medication-sparing effect, it may lead to an improvement in quality of life. The objective of the study is to compare the effect of antihypertensive drug therapy and balloon angioplasty on quality of life in patients with hypertension and renal artery stenosis. We compared the quality of life in 56 patients randomised to balloon angioplasty to that in 50 patients randomised to antihypertensive drug therapy after 3 and 12 months of follow-up. Quality of life was measured using a questionnaire on physical symptoms associated with hypertension and antihypertensive drugs, and two generic health questionnaires (MOS Survey and EuroQol instrument). After follow-up, the patients who underwent angioplasty used less antihypertensive drugs than the patients who were treated with antihypertensive drugs only (mean±s.d., 1.9±0.9
vs
2.5±1.0 drugs after 3 months,
P
=0.002). They reported similar physical complaints, however, and a similar quality of life. The results after 12 months of follow-up were the same. In conclusion, for patients with hypertension and renal artery stenosis, the decrease in antihypertensive medication after intervention is too small to lead to a detectable improvement in quality of life.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>15759023</pmid><doi>10.1038/sj.jhh.1001847</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; SpringerLink Journals - AutoHoldings |
subjects | Aged Angioplasty Angioplasty, Balloon Antihypertensive agents Antihypertensive Agents - therapeutic use Antihypertensives Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cardiovascular system Care and treatment Clinical manifestations. Epidemiology. Investigative techniques. Etiology Diuretics Drug therapy Epidemiology Female Follow-Up Studies Health Administration Health aspects Humans Hypertension Hypertension - drug therapy Hypertension - etiology Hypertension - physiopathology Male Medical sciences Medicine Medicine & Public Health Middle Aged original-article Patient outcomes Patients Pharmacology. Drug treatments Public Health Quality of Life Renal artery Renal artery obstruction Renal Artery Obstruction - complications Renal Artery Obstruction - physiopathology Renal Artery Obstruction - therapy Stenosis Stents Surveys and Questionnaires |
title | The effect of treatment on health-related quality of life in patients with hypertension and renal artery stenosis |
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