Lymphatic endothelium-specific hyaluronan receptor LYVE-1 is expressed by stabilin-1+, F4/80+, CD11b+ macrophages in malignant tumours and wound healing tissue in vivo and in bone marrow cultures in vitro: implications for the assessment of lymphangiogenesis

Lymphangiogenesis is a novel prognostic parameter for several cancers that is preferentially quantified by immunohistochemistry of the lymphatic endothelium‐specific hyaluronan receptor LYVE‐1. Recently, the specificity of LYVE‐1 was challenged by serendipitous observations of LYVE‐1 expression in r...

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Veröffentlicht in:	The Journal of pathology 2006-05, Vol.209 (1), p.67-77
Hauptverfasser:	Schledzewski, K, Falkowski, M, Moldenhauer, G, Metharom, P, Kzhyshkowska, J, Ganss, R, Demory, A, Falkowska-Hansen, B, Kurzen, H, Ugurel, S, Geginat, G, Arnold, B, Goerdt, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Differentiation - analysis Bone Marrow Cells - metabolism CD11b Antigen - analysis Cell Adhesion Molecules, Neuronal - metabolism Cells, Cultured Disease Models, Animal endothelial-like Endothelium, Lymphatic - metabolism Female Glycoproteins - metabolism lymphangiogenesis Lymphangiogenesis - physiology LYVE-1 macrophages Macrophages - metabolism Macrophages - physiology Melanoma - metabolism Melanoma - pathology Melanoma - secondary Membrane Glycoproteins - metabolism Mice Mice, Inbred C57BL Neoplasm Proteins - metabolism stabilin-1 Tumor Cells, Cultured Vesicular Transport Proteins Wound Healing - physiology
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