Examination of the Premelting Transition of DNA A-Tracts Using a Fluorescent Adenosine Analogue

The fluorescent adenosine analogue 4-amino-8-(2-deoxy-β-d-ribofuranosyl)-5‘-O-dimethoxytrityl-6-methyl-7(8H)-pteridone (6MAP) has been used to perform residue specific analyses of DNA A-tracts during the premelting transition. DNA A-tracts, which exhibit sequence-induced curvature, adopt a B-DNA con...

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