Albumin Binding to FcRn: Distinct from the FcRn−IgG Interaction

The MHC-related Fc receptor for IgG (FcRn) protects albumin and IgG from degradation by binding both proteins with high affinity at low pH in the acid endosome and diverting both from a lysosomal pathway, returning them to the extracellular compartment. Immunoblotting and surface plasmon resonance s...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemistry (Easton) 2006-04, Vol.45 (15), p.4983-4990
Hauptverfasser:	Chaudhury, Chaity, Brooks, Charles L, Carter, Daniel C, Robinson, John M, Anderson, Clark L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CHO Cells Cricetinae Histocompatibility Antigens Class I - genetics Histocompatibility Antigens Class I - metabolism Humans Hydrogen-Ion Concentration Immunoblotting Immunoglobulin G - immunology Immunoglobulin G - metabolism Ligands Protein Binding - physiology Receptors, Fc - genetics Receptors, Fc - metabolism Serum Albumin - metabolism Surface Plasmon Resonance
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!