Efficient calculation of interval scores for DNA copy number data analysis

DNA amplifications and deletions characterize cancer genome and are often related to disease evolution. Microarray-based techniques for measuring these DNA copy-number changes use fluorescence ratios at arrayed DNA elements (BACs, cDNA, or oligonucleotides) to provide signals at high resolution, in...

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Veröffentlicht in:	Journal of computational biology 2006-03, Vol.13 (2), p.215-228
Hauptverfasser:	Lipson, Doron, Aumann, Yonatan, Ben-Dor, Amir, Linial, Nathan, Yakhini, Zohar
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Breast Neoplasms - genetics Chromosome Aberrations DNA - chemistry Female Gene Dosage Genetic Markers Humans In Situ Hybridization, Fluorescence Nucleic Acid Hybridization - methods Tumor Cells, Cultured
Online-Zugang:	Volltext
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