Expression of SRY proteins in both normal and sex‐reversed XY fetal mouse gonads

Sry, a single‐copy gene on the Y‐chromosome, acts dominantly to trigger differentiation of a testis from a gonadal primordium that otherwise develops into an ovary in mammals. Sry encodes a protein with a DNA‐binding domain and probably acts as a transcription factor. However, the mode of SRY action...

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Veröffentlicht in:Developmental dynamics 2005-06, Vol.233 (2), p.612-622
Hauptverfasser: Taketo, Teruko, Lee, Chung‐Hae, Zhang, Jianqing, Li, Yunmin, Lee, Chi‐Yu Gregory, Lau, Yun‐Fai Chris
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Sprache:eng
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