The Relationship of Molecular Markers of p53 Function and Angiogenesis to Prognosis of Stage I Epithelial Ovarian Cancer

Purpose: Multiple angiogenic factors may influence tumor progression and metastasis. Several are modified by the p53 gene. We sought to identify molecular markers for high-risk stage I epithelial ovarian cancers. Experimental Design: Seventy-seven consecutive stage I epithelial ovarian cancers were...

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Veröffentlicht in:	Clinical cancer research 2005-05, Vol.11 (10), p.3733-3742
Hauptverfasser:	GOODHEART, Michael J, RITCHIE, Justine M, ROSE, Stephen L, FRUEHAUF, John P, DEYOUNG, Barry R, BULLER, Richard E
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences Chemotherapy, Adjuvant Disease-Free Survival DNA Mutational Analysis Female Female genital diseases Genes, p53 Gynecology. Andrology. Obstetrics Humans Immunohistochemistry Medical sciences Middle Aged molecular markers Neoplasm Metastasis Neoplasm Recurrence, Local - genetics Neovascularization, Pathologic Ovarian Neoplasms - blood supply Ovarian Neoplasms - drug therapy Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology p53 Pharmacology. Drug treatments Prognosis Regression Analysis Risk Factors stage I epithelial ovarian cancer Tumors
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