Investigation of Genetic Variants of Genes of the Hemochromatosis Pathway and Their Role in Breast Cancer

Iron overload has been noticed as a feature of human breast cancer. Cellular iron uptake is regulated by the hemochromatosis and transferrin receptor system, mutations of which cause the iron storage disease hereditary hemochromatosis. To understand the role of hemochromatosis and transferrin recept...

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Veröffentlicht in:	Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2005-05, Vol.14 (5), p.1102-1107
Hauptverfasser:	ABRAHAM, Benny K, JUSTENHOVEN, Christina, HAAS, Susanne, BROD, Sandra, OBERKANINS, Christian, HAMANN, Ute, BRAUCH, Hiltrud, PESCH, Beate, HARTH, Volker, WEIRICH, Gregor, BAISCH, Christian, RABSTEIN, Sylvia, KO, Yon-Dschun, BRÜNING, Thomas, FISCHER, Hans-Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Breast cancer Breast Neoplasms - blood Breast Neoplasms - epidemiology Breast Neoplasms - genetics Case-Control Studies Female FPN1 Gene Frequency Genetic Variation Genotype Germany - epidemiology Gynecology. Andrology. Obstetrics hemochromatosis Hemochromatosis - epidemiology Hemochromatosis - genetics HFE Humans Incidence Iron - metabolism Logistic Models Mammary gland diseases Medical sciences Menopause Middle Aged Polymerase Chain Reaction Polymorphism, Genetic Risk Factors TFR Tumors
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