Expression of functional aromatase in the epididymis: Role of androgens and LH in modulation of expression and activity

The primary source of 17beta-estradiol (E2) in the male is the testis, which expresses the enzyme complex aromatase that is involved in E2 biosynthesis. However, recent evidences suggest that the epididymis is also capable of E2 biosynthesis. Our results demonstrate the presence of cytochrome P450 a...

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Veröffentlicht in:	Molecular and cellular endocrinology 2006-04, Vol.249 (1-2), p.40-50
Hauptverfasser:	Shayu, D., Rao, A.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	17-Hydroxysteroid Dehydrogenases - metabolism 17β-HSDI Androgens - physiology Animals Aromatase - genetics Aromatase - metabolism Chorionic Gonadotropin - metabolism Cyclic AMP - biosynthesis Epididymis - enzymology Epididymis - metabolism Estradiol - biosynthesis Flutamide Gene Expression Regulation LH receptor Luteinizing Hormone - physiology Male Rats Receptors, LH - genetics Receptors, LH - metabolism RNA, Messenger - metabolism
Online-Zugang:	Volltext
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