Synthesis and antifungal activity of 2/3-arylthio- and 2,3-bis(arylthio)-5-hydroxy-/5-methoxy-1,4-naphthoquinones

2/3-Arylthio- and 2,3-bis(arylthio)-5-hydroxy-/5-methoxy-1,4-naphthoquinones 5– 9 were synthesized and tested for in vitro antifungal activity against Candida species and Aspergillus niger. The synthesized compounds 5– 9 generally showed good activities against Candida albicans and C. tropicalis. Th...

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Veröffentlicht in:	European journal of medicinal chemistry 2005-05, Vol.40 (5), p.438-444
Hauptverfasser:	Ryu, Chung-Kyu, Shim, Ju-Yeon, Chae, Mi Jin, Choi, Ik Hwa, Han, Ja-Young, Jung, Ok-Jai, Lee, Jung Yoon, Jeong, Seong Hee
Format:	Artikel
Sprache:	eng
Schlagworte:	1,4-Naphthoquinones Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal activity Antifungal agents Antifungal Agents - chemical synthesis Antifungal Agents - chemistry Antifungal Agents - pharmacology Aspergillus niger - drug effects Biological and medical sciences Candida - drug effects Cell Line, Tumor Fungi Humans Juglone Magnetic Resonance Spectroscopy Mass Spectrometry Medical sciences Microbial Sensitivity Tests Molecular Structure Naphthoquinones - chemical synthesis Naphthoquinones - chemistry Naphthoquinones - pharmacology Pharmacology. Drug treatments Spectrophotometry, Infrared
Online-Zugang:	Volltext
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