DNA strand break: Structural and electrostatic properties studied by molecular dynamics simulation

Due to their lethal consequences and a relatively high probability of introduction of repair errors and mutations, single and double strand breaks are among the most important and dangerous DNA lesions. However, the mechanisms of their recognition and repair processes are only poorly known at presen...

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Veröffentlicht in:Computational biology and chemistry 2006-04, Vol.30 (2), p.112-119
Hauptverfasser: Bunta, Juraj Kotulic, Laaksonen, Aatto, Pinak, Miroslav, Nemoto, Toshiyuki
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Sprache:eng
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