Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine

Gene expression analysis may help the management of cancer patients, allowing the selection of subjects responding to treatment. The aim of this study was the characterization of expression pattern of genes involved in gemcitabine activity in pancreas tumor specimens and its correlation with treatme...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2006-04, Vol.66 (7), p.3928-3935
Hauptverfasser:	GIOVANNETTI, Elisa, DEL TACCA, Mario, IANNOPOLLO, Mauro, BEVILACQUA, Generoso, MOSCA, Franco, DANESI, Romano, MEY, Valentina, FUND, Niccola, NANNIZZI, Sara, RICCI, Sergio, ORLANDINI, Cinzia, BOGGI, Ugo, CAMPANI, Daniela, DEL CHIARO, Marco
Format:	Artikel
Sprache:	eng
Schlagworte:	5'-Nucleotidase - biosynthesis 5'-Nucleotidase - genetics Adult Aged Aged, 80 and over Antineoplastic agents Biological and medical sciences Cell Line, Tumor Cytidine Deaminase - biosynthesis Cytidine Deaminase - genetics Deoxycytidine - analogs & derivatives Deoxycytidine - therapeutic use Deoxycytidine Kinase - biosynthesis Deoxycytidine Kinase - genetics Equilibrative Nucleoside Transporter 1 - biosynthesis Equilibrative Nucleoside Transporter 1 - genetics Female Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Humans Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Middle Aged Pancreatic Neoplasms - drug therapy Pancreatic Neoplasms - genetics Pancreatic Neoplasms - metabolism Pharmacology. Drug treatments Predictive Value of Tests Prognosis Reverse Transcriptase Polymerase Chain Reaction Ribonucleoside Diphosphate Reductase - biosynthesis Ribonucleoside Diphosphate Reductase - genetics Transcriptional Activation Treatment Outcome Tumor Suppressor Proteins - biosynthesis Tumor Suppressor Proteins - genetics Tumors
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