Inhibition studies on salicylate synthase

Inhibition studies on salicylate synthase

Analogues of chorismate and isochorismate were designed and tested as potential inhibitors in the first inhibition study against a salicylate synthase.

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Veröffentlicht in:Organic & biomolecular chemistry 2005-05, Vol.3 (10), p.1825-1827
Hauptverfasser: Payne, Richard J, Kerbarh, Olivier, Miguel, Ricardo Nunez, Abell, Andrew D, Abell, Chris
Format: Artikel
Sprache:eng
Schlagworte:
Bacteria - enzymology
Chorismic Acid - chemistry
Chorismic Acid - pharmacology
Cyclohexenes
Enzyme Inhibitors - pharmacology
Lyases - antagonists & inhibitors
Lyases - chemistry
Models, Molecular
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Zusammenfassung:Analogues of chorismate and isochorismate were designed and tested as potential inhibitors in the first inhibition study against a salicylate synthase.
ISSN:1477-0520
1477-0539
DOI:10.1039/b503800f