Study on the susceptibility of Sahel goats to experimental Trypanosoma vivax infection
Sahel goats, also known as Borno whites are found in the northern semi-arid, tsetse free Sahel region of Nigeria. They are transported alongside cattle from this zone to all other zones in the country, including the tsetse-infested zones, for commercial purposes and are kept for some time in these t...
Gespeichert in:
| Veröffentlicht in: | Veterinary parasitology 2006-04, Vol.137 (3), p.210-213 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 213 |
|---|---|
| container_issue | 3 |
| container_start_page | 210 |
| container_title | Veterinary parasitology |
| container_volume | 137 |
| creator | Akinwale, Olaoluwa P. Nock, Ishaya H. Esievo, King A.N. Edeghere, Henry U. Olukosi, Yetunde A. |
| description | Sahel goats, also known as Borno whites are found in the northern semi-arid, tsetse free Sahel region of Nigeria. They are transported alongside cattle from this zone to all other zones in the country, including the tsetse-infested zones, for commercial purposes and are kept for some time in these tsetse-infested zones until they are sold. This study therefore assessed the susceptibility of this breed of goats to trypanosome infection and its response to treatment with Berenil. Six bucks were inoculated intravenously with
Trypanosoma vivax through the jugular vein while two served as uninfected control. The mean pre-patent period was 4.5 days and increasing parasitaemia followed the establishment of infection. Onset of parasitaemia was associated with increase in rectal temperature in all the infected goats and the temperature peak coincided with the only parasitaemic peak second week post-infection. The infected goats were treated with Berenil (Hoechst, Germany) 3.5
mg/kg body weight at 4 weeks post-infection. The packed cell volume (PCV) continued to fall from a mean 30.73
±
0.01% pre-infection to a mean 13.21
±
0.18% at 1 week post-treatment. Deaths were recorded for 4 of the infected goats 1 week post-treatment while the remaining two died 2 weeks post-treatment, not responding to treatment. |
| doi_str_mv | 10.1016/j.vetpar.2006.01.032 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67823302</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0304401706000392</els_id><sourcerecordid>19379708</sourcerecordid><originalsourceid>FETCH-LOGICAL-c415t-1093f7fa25761a696b6ecc9e1fd747997c254e048f8d5632ef4b2c56ebc4f3b23</originalsourceid><addsrcrecordid>eNqFkEtv1DAURi0EokPhHyDwil2G60fsZIOEKl5SJRbTsrUc57r1KBMH2xl1_j0ZZSR2sLrS1fnu4xDylsGWAVMf99sjlsmmLQdQW2BbEPwZ2bBGi4rXNTwnGxAgKwlMX5FXOe8BQILSL8kVU7LVUrIN-bUrc3-icaTlEWmes8OphC4MoSxdT3f2EQf6EG3JtESKTxOmcMCx2IHepdNkx5jjwdJjONonGkaProQ4viYvvB0yvrnUa3L_9cvdzffq9ue3HzefbysnWV0qBq3w2ltea8WsalWn0LkWme-11G2rHa8lgmx809dKcPSy465W2DnpRcfFNfmwzp1S_D1jLuYQlheGwY4Y52yUbrgQ8H-QtUK3GpoFlCvoUsw5oTfT8rBNJ8PAnMWbvVnFm7N4A8ws4pfYu8v8uTtg_zd0Mb0A71fA22jsQwrZ3O84MAEMdC3EefOnlcBF2DFgMtkFHB32IS1WTR_Dv2_4A6GHoFo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>19379708</pqid></control><display><type>article</type><title>Study on the susceptibility of Sahel goats to experimental Trypanosoma vivax infection</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Akinwale, Olaoluwa P. ; Nock, Ishaya H. ; Esievo, King A.N. ; Edeghere, Henry U. ; Olukosi, Yetunde A.</creator><creatorcontrib>Akinwale, Olaoluwa P. ; Nock, Ishaya H. ; Esievo, King A.N. ; Edeghere, Henry U. ; Olukosi, Yetunde A.</creatorcontrib><description>Sahel goats, also known as Borno whites are found in the northern semi-arid, tsetse free Sahel region of Nigeria. They are transported alongside cattle from this zone to all other zones in the country, including the tsetse-infested zones, for commercial purposes and are kept for some time in these tsetse-infested zones until they are sold. This study therefore assessed the susceptibility of this breed of goats to trypanosome infection and its response to treatment with Berenil. Six bucks were inoculated intravenously with
Trypanosoma vivax through the jugular vein while two served as uninfected control. The mean pre-patent period was 4.5 days and increasing parasitaemia followed the establishment of infection. Onset of parasitaemia was associated with increase in rectal temperature in all the infected goats and the temperature peak coincided with the only parasitaemic peak second week post-infection. The infected goats were treated with Berenil (Hoechst, Germany) 3.5
mg/kg body weight at 4 weeks post-infection. The packed cell volume (PCV) continued to fall from a mean 30.73
±
0.01% pre-infection to a mean 13.21
±
0.18% at 1 week post-treatment. Deaths were recorded for 4 of the infected goats 1 week post-treatment while the remaining two died 2 weeks post-treatment, not responding to treatment.</description><identifier>ISSN: 0304-4017</identifier><identifier>EISSN: 1873-2550</identifier><identifier>DOI: 10.1016/j.vetpar.2006.01.032</identifier><identifier>PMID: 16497441</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>African trypanosomiasis ; Animals ; diminazene ; Diminazene - analogs & derivatives ; Diminazene - therapeutic use ; disease resistance ; Disease Susceptibility ; drug therapy ; Experimental ; experimental infection ; goat breeds ; Goat Diseases - drug therapy ; Goat Diseases - epidemiology ; Goat Diseases - mortality ; Goats ; hematocrit ; infection ; Male ; Nigeria - epidemiology ; parasitemia ; Parasitemia - drug therapy ; Parasitemia - epidemiology ; Parasitemia - mortality ; Parasitemia - veterinary ; prepatent period ; Random Allocation ; Sahel goats ; Susceptibility ; Treatment Outcome ; Trypanocidal Agents - therapeutic use ; trypanocides ; Trypanosoma ; Trypanosoma vivax ; Trypanosoma vivax - pathogenicity ; Trypanosoma vivax infection ; Trypanosomiasis, African - drug therapy ; Trypanosomiasis, African - epidemiology ; Trypanosomiasis, African - mortality ; Trypanosomiasis, African - veterinary ; trypanotolerance</subject><ispartof>Veterinary parasitology, 2006-04, Vol.137 (3), p.210-213</ispartof><rights>2006 Elsevier B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-1093f7fa25761a696b6ecc9e1fd747997c254e048f8d5632ef4b2c56ebc4f3b23</citedby><cites>FETCH-LOGICAL-c415t-1093f7fa25761a696b6ecc9e1fd747997c254e048f8d5632ef4b2c56ebc4f3b23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.vetpar.2006.01.032$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,782,786,3554,27933,27934,46004</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16497441$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Akinwale, Olaoluwa P.</creatorcontrib><creatorcontrib>Nock, Ishaya H.</creatorcontrib><creatorcontrib>Esievo, King A.N.</creatorcontrib><creatorcontrib>Edeghere, Henry U.</creatorcontrib><creatorcontrib>Olukosi, Yetunde A.</creatorcontrib><title>Study on the susceptibility of Sahel goats to experimental Trypanosoma vivax infection</title><title>Veterinary parasitology</title><addtitle>Vet Parasitol</addtitle><description>Sahel goats, also known as Borno whites are found in the northern semi-arid, tsetse free Sahel region of Nigeria. They are transported alongside cattle from this zone to all other zones in the country, including the tsetse-infested zones, for commercial purposes and are kept for some time in these tsetse-infested zones until they are sold. This study therefore assessed the susceptibility of this breed of goats to trypanosome infection and its response to treatment with Berenil. Six bucks were inoculated intravenously with
Trypanosoma vivax through the jugular vein while two served as uninfected control. The mean pre-patent period was 4.5 days and increasing parasitaemia followed the establishment of infection. Onset of parasitaemia was associated with increase in rectal temperature in all the infected goats and the temperature peak coincided with the only parasitaemic peak second week post-infection. The infected goats were treated with Berenil (Hoechst, Germany) 3.5
mg/kg body weight at 4 weeks post-infection. The packed cell volume (PCV) continued to fall from a mean 30.73
±
0.01% pre-infection to a mean 13.21
±
0.18% at 1 week post-treatment. Deaths were recorded for 4 of the infected goats 1 week post-treatment while the remaining two died 2 weeks post-treatment, not responding to treatment.</description><subject>African trypanosomiasis</subject><subject>Animals</subject><subject>diminazene</subject><subject>Diminazene - analogs & derivatives</subject><subject>Diminazene - therapeutic use</subject><subject>disease resistance</subject><subject>Disease Susceptibility</subject><subject>drug therapy</subject><subject>Experimental</subject><subject>experimental infection</subject><subject>goat breeds</subject><subject>Goat Diseases - drug therapy</subject><subject>Goat Diseases - epidemiology</subject><subject>Goat Diseases - mortality</subject><subject>Goats</subject><subject>hematocrit</subject><subject>infection</subject><subject>Male</subject><subject>Nigeria - epidemiology</subject><subject>parasitemia</subject><subject>Parasitemia - drug therapy</subject><subject>Parasitemia - epidemiology</subject><subject>Parasitemia - mortality</subject><subject>Parasitemia - veterinary</subject><subject>prepatent period</subject><subject>Random Allocation</subject><subject>Sahel goats</subject><subject>Susceptibility</subject><subject>Treatment Outcome</subject><subject>Trypanocidal Agents - therapeutic use</subject><subject>trypanocides</subject><subject>Trypanosoma</subject><subject>Trypanosoma vivax</subject><subject>Trypanosoma vivax - pathogenicity</subject><subject>Trypanosoma vivax infection</subject><subject>Trypanosomiasis, African - drug therapy</subject><subject>Trypanosomiasis, African - epidemiology</subject><subject>Trypanosomiasis, African - mortality</subject><subject>Trypanosomiasis, African - veterinary</subject><subject>trypanotolerance</subject><issn>0304-4017</issn><issn>1873-2550</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtv1DAURi0EokPhHyDwil2G60fsZIOEKl5SJRbTsrUc57r1KBMH2xl1_j0ZZSR2sLrS1fnu4xDylsGWAVMf99sjlsmmLQdQW2BbEPwZ2bBGi4rXNTwnGxAgKwlMX5FXOe8BQILSL8kVU7LVUrIN-bUrc3-icaTlEWmes8OphC4MoSxdT3f2EQf6EG3JtESKTxOmcMCx2IHepdNkx5jjwdJjONonGkaProQ4viYvvB0yvrnUa3L_9cvdzffq9ue3HzefbysnWV0qBq3w2ltea8WsalWn0LkWme-11G2rHa8lgmx809dKcPSy465W2DnpRcfFNfmwzp1S_D1jLuYQlheGwY4Y52yUbrgQ8H-QtUK3GpoFlCvoUsw5oTfT8rBNJ8PAnMWbvVnFm7N4A8ws4pfYu8v8uTtg_zd0Mb0A71fA22jsQwrZ3O84MAEMdC3EefOnlcBF2DFgMtkFHB32IS1WTR_Dv2_4A6GHoFo</recordid><startdate>20060430</startdate><enddate>20060430</enddate><creator>Akinwale, Olaoluwa P.</creator><creator>Nock, Ishaya H.</creator><creator>Esievo, King A.N.</creator><creator>Edeghere, Henry U.</creator><creator>Olukosi, Yetunde A.</creator><general>Elsevier B.V</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SS</scope><scope>M7N</scope><scope>7X8</scope></search><sort><creationdate>20060430</creationdate><title>Study on the susceptibility of Sahel goats to experimental Trypanosoma vivax infection</title><author>Akinwale, Olaoluwa P. ; Nock, Ishaya H. ; Esievo, King A.N. ; Edeghere, Henry U. ; Olukosi, Yetunde A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-1093f7fa25761a696b6ecc9e1fd747997c254e048f8d5632ef4b2c56ebc4f3b23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>African trypanosomiasis</topic><topic>Animals</topic><topic>diminazene</topic><topic>Diminazene - analogs & derivatives</topic><topic>Diminazene - therapeutic use</topic><topic>disease resistance</topic><topic>Disease Susceptibility</topic><topic>drug therapy</topic><topic>Experimental</topic><topic>experimental infection</topic><topic>goat breeds</topic><topic>Goat Diseases - drug therapy</topic><topic>Goat Diseases - epidemiology</topic><topic>Goat Diseases - mortality</topic><topic>Goats</topic><topic>hematocrit</topic><topic>infection</topic><topic>Male</topic><topic>Nigeria - epidemiology</topic><topic>parasitemia</topic><topic>Parasitemia - drug therapy</topic><topic>Parasitemia - epidemiology</topic><topic>Parasitemia - mortality</topic><topic>Parasitemia - veterinary</topic><topic>prepatent period</topic><topic>Random Allocation</topic><topic>Sahel goats</topic><topic>Susceptibility</topic><topic>Treatment Outcome</topic><topic>Trypanocidal Agents - therapeutic use</topic><topic>trypanocides</topic><topic>Trypanosoma</topic><topic>Trypanosoma vivax</topic><topic>Trypanosoma vivax - pathogenicity</topic><topic>Trypanosoma vivax infection</topic><topic>Trypanosomiasis, African - drug therapy</topic><topic>Trypanosomiasis, African - epidemiology</topic><topic>Trypanosomiasis, African - mortality</topic><topic>Trypanosomiasis, African - veterinary</topic><topic>trypanotolerance</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Akinwale, Olaoluwa P.</creatorcontrib><creatorcontrib>Nock, Ishaya H.</creatorcontrib><creatorcontrib>Esievo, King A.N.</creatorcontrib><creatorcontrib>Edeghere, Henry U.</creatorcontrib><creatorcontrib>Olukosi, Yetunde A.</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><jtitle>Veterinary parasitology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Akinwale, Olaoluwa P.</au><au>Nock, Ishaya H.</au><au>Esievo, King A.N.</au><au>Edeghere, Henry U.</au><au>Olukosi, Yetunde A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Study on the susceptibility of Sahel goats to experimental Trypanosoma vivax infection</atitle><jtitle>Veterinary parasitology</jtitle><addtitle>Vet Parasitol</addtitle><date>2006-04-30</date><risdate>2006</risdate><volume>137</volume><issue>3</issue><spage>210</spage><epage>213</epage><pages>210-213</pages><issn>0304-4017</issn><eissn>1873-2550</eissn><abstract>Sahel goats, also known as Borno whites are found in the northern semi-arid, tsetse free Sahel region of Nigeria. They are transported alongside cattle from this zone to all other zones in the country, including the tsetse-infested zones, for commercial purposes and are kept for some time in these tsetse-infested zones until they are sold. This study therefore assessed the susceptibility of this breed of goats to trypanosome infection and its response to treatment with Berenil. Six bucks were inoculated intravenously with
Trypanosoma vivax through the jugular vein while two served as uninfected control. The mean pre-patent period was 4.5 days and increasing parasitaemia followed the establishment of infection. Onset of parasitaemia was associated with increase in rectal temperature in all the infected goats and the temperature peak coincided with the only parasitaemic peak second week post-infection. The infected goats were treated with Berenil (Hoechst, Germany) 3.5
mg/kg body weight at 4 weeks post-infection. The packed cell volume (PCV) continued to fall from a mean 30.73
±
0.01% pre-infection to a mean 13.21
±
0.18% at 1 week post-treatment. Deaths were recorded for 4 of the infected goats 1 week post-treatment while the remaining two died 2 weeks post-treatment, not responding to treatment.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>16497441</pmid><doi>10.1016/j.vetpar.2006.01.032</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0304-4017 |
| ispartof | Veterinary parasitology, 2006-04, Vol.137 (3), p.210-213 |
| issn | 0304-4017 1873-2550 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67823302 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | African trypanosomiasis Animals diminazene Diminazene - analogs & derivatives Diminazene - therapeutic use disease resistance Disease Susceptibility drug therapy Experimental experimental infection goat breeds Goat Diseases - drug therapy Goat Diseases - epidemiology Goat Diseases - mortality Goats hematocrit infection Male Nigeria - epidemiology parasitemia Parasitemia - drug therapy Parasitemia - epidemiology Parasitemia - mortality Parasitemia - veterinary prepatent period Random Allocation Sahel goats Susceptibility Treatment Outcome Trypanocidal Agents - therapeutic use trypanocides Trypanosoma Trypanosoma vivax Trypanosoma vivax - pathogenicity Trypanosoma vivax infection Trypanosomiasis, African - drug therapy Trypanosomiasis, African - epidemiology Trypanosomiasis, African - mortality Trypanosomiasis, African - veterinary trypanotolerance |
| title | Study on the susceptibility of Sahel goats to experimental Trypanosoma vivax infection |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-02T16%3A40%3A52IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Study%20on%20the%20susceptibility%20of%20Sahel%20goats%20to%20experimental%20Trypanosoma%20vivax%20infection&rft.jtitle=Veterinary%20parasitology&rft.au=Akinwale,%20Olaoluwa%20P.&rft.date=2006-04-30&rft.volume=137&rft.issue=3&rft.spage=210&rft.epage=213&rft.pages=210-213&rft.issn=0304-4017&rft.eissn=1873-2550&rft_id=info:doi/10.1016/j.vetpar.2006.01.032&rft_dat=%3Cproquest_cross%3E19379708%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=19379708&rft_id=info:pmid/16497441&rft_els_id=S0304401706000392&rfr_iscdi=true |