Dynamic changes of GAD65 autoantibody epitope specificities in individuals at risk of developing type 1 diabetes

Progression to type 1 diabetes is associated with intramolecular epitope spreading to disease-specific antibody epitopes located in the middle region of glutamic acid decarboxylase 65 (GAD65). The relationship between intramolecular epitope spreading of autoantibodies specific to GAD65 in relation t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Diabetologia 2005-05, Vol.48 (5), p.922-930
Hauptverfasser:	SCHLOSSER, M, BANGA, J. P, MADEC, A. M, BINDER, K. A, STREBELOW, M, RJASANOWSKI, I, WASSMUTH, R, GILLIAM, L. K, LUO, D, HAMPE, C. S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antibodies Antigens Autoantibodies - blood Biological and medical sciences Child Diabetes Diabetes Mellitus, Type 1 - epidemiology Diabetes Mellitus, Type 1 - immunology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Epitopes - analysis Female Genotype Glutamate Decarboxylase - immunology HLA Antigens Humans Immunoglobulin Fab Fragments - immunology Insulin Isoenzymes - immunology Longitudinal studies Major Histocompatibility Complex Male Medical sciences Medicine Risk Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!