Microfabrication of encoded microparticle array for multiplexed DNA hybridization detection

Microfabrication of encoded microparticle array for multiplexed DNA hybridization detection

A strategy for the high-sensitivity, high-selectivity, and multiplexed detection of oligonucleotide hybridizations has been developed with an encoded Ni microparticle random array that was manufactured by a "top-down" approach using micromachining and microfabrication techniques.

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Bibliographische Detailangaben
Veröffentlicht in:Chemical communications (Cambridge, England) England), 2005-05 (19), p.2448-2450
Hauptverfasser: Zhi, Zheng-Liang, Morita, Yasutaka, Yamamura, Shouhei, Tamiya, Eiichi
Format: Artikel
Sprache:eng
Schlagworte:
Biotin - chemistry
DNA - chemistry
Fluorescein-5-isothiocyanate
Fluorescent Dyes
Microscopy, Fluorescence
Nanoparticles
Nanotechnology - methods
Nickel - chemistry
Nucleic Acid Hybridization
Oligonucleotides - chemistry
Spectrometry, Fluorescence
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Beschreibung
Zusammenfassung:A strategy for the high-sensitivity, high-selectivity, and multiplexed detection of oligonucleotide hybridizations has been developed with an encoded Ni microparticle random array that was manufactured by a "top-down" approach using micromachining and microfabrication techniques.
ISSN:1359-7345
1364-548X
DOI:10.1039/b501146a