Recent Developments in Mass Spectrometry for the Characterization of Nucleosides, Nucleotides, Oligonucleotides, and Nucleic Acids

Recent Developments in Mass Spectrometry for the Characterization of Nucleosides, Nucleotides, Oligonucleotides, and Nucleic Acids

Tremendous efforts have been made to develop and implement methodologies and mass spectrometric methods for the study of the monomeric constituents of nucleic acids. Banoub, et all put in perspective the progress in current biotechnological research in this area by highlighting the most popular ioni...

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Veröffentlicht in:Chemical reviews 2005-05, Vol.105 (5), p.1869-1916
Hauptverfasser: Banoub, Joseph H, Newton, Russell P, Esmans, Eddy, Ewing, David F, Mackenzie, Grahame
Format: Artikel
Sprache:eng
Schlagworte:
Biotechnology
Cellular biology
Chemistry
Mass Spectrometry
Molecular Structure
Nucleic Acids - chemistry
Nucleosides - chemistry
Nucleotides - chemistry
Oligonucleotides - chemistry
Progress
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container_end_page 1916
container_issue 5
container_start_page 1869
container_title Chemical reviews
container_volume 105
creator Banoub, Joseph H
Newton, Russell P
Esmans, Eddy
Ewing, David F
Mackenzie, Grahame
description Tremendous efforts have been made to develop and implement methodologies and mass spectrometric methods for the study of the monomeric constituents of nucleic acids. Banoub, et all put in perspective the progress in current biotechnological research in this area by highlighting the most popular ionization methods, especially when used in conjunction with tandem mass spectrometry, and illustrating the diversity of strategies employed in the characterization and sequencing of DNA and RNA oligomers.
doi_str_mv 10.1021/cr030040w
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subjects Biotechnology
Cellular biology
Chemistry
Mass Spectrometry
Molecular Structure
Nucleic Acids - chemistry
Nucleosides - chemistry
Nucleotides - chemistry
Oligonucleotides - chemistry
Progress
title Recent Developments in Mass Spectrometry for the Characterization of Nucleosides, Nucleotides, Oligonucleotides, and Nucleic Acids
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