A randomized trial of ganciclovir versus ganciclovir plus immune globulin for prophylaxis against epstein-barr virus related posttransplant lymphoproliferative disorder

Transplant recipients who are Epstein-Barr virus (EBV)-seronegative and receive organs from seropositive donors (EBV D+/R-) are at increased risk for posttransplant lymphoproliferative disorder (PTLD) and may benefit from antiviral prophylaxis. We performed a multi-center trial assessing two differe...

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Veröffentlicht in:	Transplantation 2006-03, Vol.81 (6), p.856-861
Hauptverfasser:	HUMAR, Atul, HEBERT, Diane, DELE DAVIES, H, HUMOR, Abhinav, STEPHENS, Derek, O'DOHERTY, Brenda, ALLEN, Upton
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antiviral Agents - therapeutic use Biological and medical sciences Child Child, Preschool Cytomegalovirus Infections - prevention & control Epstein-Barr virus Epstein-Barr Virus Infections - prevention & control Female Fundamental and applied biological sciences. Psychology Fundamental immunology Ganciclovir - administration & dosage Ganciclovir - therapeutic use Hematologic and hematopoietic diseases Herpesvirus 4, Human - isolation & purification Humans Immunoglobulins - administration & dosage Infant Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoproliferative Disorders - prevention & control Male Medical sciences Middle Aged Organ Transplantation - adverse effects Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tissue, organ and graft immunology Viral Load
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