Contribution of melanocortin-1 receptor gene variants to sporadic cutaneous melanoma risk in a population in central Italy: a case-control study

The melanocortin-1 receptor (MC1R) gene is a key determinant of the physiological variation in human skin pigmentation. It is highly polymorphic, and specific MC1R allelic variants have been shown to be low-penetrance melanoma susceptibility alleles. We investigated the contribution of the MC1R geno...

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Veröffentlicht in:	Melanoma research 2006-04, Vol.16 (2), p.175-182
Hauptverfasser:	Fargnoli, Maria Concetta, Altobelli, Emma, Keller, Gisela, Chimenti, Sergio, Höfler, Heinz, Peris, Ketty
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Base Sequence Case-Control Studies Female Genetic Predisposition to Disease Humans Italy Male Melanoma - genetics Middle Aged Molecular Sequence Data Polymorphism, Genetic Receptor, Melanocortin, Type 1 - genetics Reverse Transcriptase Polymerase Chain Reaction Risk Factors Skin Neoplasms - genetics
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