Role of apoA-I, ABCA1, LCAT, and SR-BI in the biogenesis of HDL

The concentration, composition, shape, and size of plasma high-density lipoprotein (HDL) are determined by numerous proteins that influence its biogenesis, remodeling, and catabolism. The discoveries of the HDL receptor (scavenger receptor class B type I, SR-BI) and the ABCA1 (ATP-binding cassette t...

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Veröffentlicht in:	Journal of molecular medicine (Berlin, Germany) Germany), 2006-04, Vol.84 (4), p.276-294
Hauptverfasser:	ZANNIS, Vassilis I, CHRONI, Angeliki, KRIEGER, Manly
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apolipoprotein A-I - metabolism Apolipoprotein A-I - physiology Atherosclerosis - prevention & control ATP Binding Cassette Transporter 1 ATP Binding Cassette Transporter, Sub-Family G ATP Binding Cassette Transporter, Sub-Family G, Member 1 ATP-Binding Cassette Transporters - metabolism ATP-Binding Cassette Transporters - physiology Biological and medical sciences Biological Transport CD36 Antigens - physiology Cholesterol, HDL - biosynthesis Dyslipidemias - genetics General aspects Humans Lipid Metabolism - physiology Lipoproteins - metabolism Medical sciences Models, Biological Models, Molecular Mutation - physiology Phosphatidylcholine-Sterol O-Acyltransferase - physiology Protein Binding Signal Transduction
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