Supercritical CO2 Extraction and Purification of Compounds with Antioxidant Activity
Supercritical fluid extraction (SCFE), based on the utilization of a fluid under supercritical conditions, is a technology suitable for extraction and purification of a variety of compounds, particularly those that have low volatility and/or are susceptible to thermal degradation. The interest in SC...
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| Veröffentlicht in: | Journal of agricultural and food chemistry 2006-04, Vol.54 (7), p.2441-2469 |
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| container_end_page | 2469 |
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| container_issue | 7 |
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| container_title | Journal of agricultural and food chemistry |
| container_volume | 54 |
| creator | Díaz-Reinoso, Beatriz Moure, Andrés Domínguez, Herminia Parajó, Juan Carlos |
| description | Supercritical fluid extraction (SCFE), based on the utilization of a fluid under supercritical conditions, is a technology suitable for extraction and purification of a variety of compounds, particularly those that have low volatility and/or are susceptible to thermal degradation. The interest in SCFE is promoted by legal limitations of conventional solvents for food and pharmaceutical uses. The physicochemical properties of supercritical CO2 (higher diffusivity, lower viscosity, and lower surface tension than conventional solvents) facilitate mass transfer and allow an environmentally friendly operation. This article presents a comprehensive compilation of data on the supercritical CO2 extraction of antioxidant compounds from vegetal materials, with particular attention to those of a phenolic nature. Aspects concerning the supercritical operation for extraction and fractionation of antioxidants compounds are considered, including equilibrium solubility of pure compounds and effects of the operational conditions on the antioxidant activity of isolated fractions. The data are compared to those reported for synthetic antioxidants and natural extracts obtained by conventional solvent extraction from vegetal matrices. Keywords: Activity; antioxidant; SCFE |
| doi_str_mv | 10.1021/jf052858j |
| format | Article |
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Aspects concerning the supercritical operation for extraction and fractionation of antioxidants compounds are considered, including equilibrium solubility of pure compounds and effects of the operational conditions on the antioxidant activity of isolated fractions. The data are compared to those reported for synthetic antioxidants and natural extracts obtained by conventional solvent extraction from vegetal matrices. Keywords: Activity; antioxidant; SCFE</description><subject>Antioxidants - isolation & purification</subject><subject>Biological and medical sciences</subject><subject>Chemical Phenomena</subject><subject>Chemistry, Physical</subject><subject>Chromatography, Supercritical Fluid - methods</subject><subject>Food engineering</subject><subject>Food industries</subject><subject>Fruit - chemistry</subject><subject>Fundamental and applied biological sciences. 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Psychology</topic><topic>General aspects</topic><topic>Hot Temperature</topic><topic>Indicators and Reagents</topic><topic>Plants - chemistry</topic><topic>Pressure</topic><topic>Solubility</topic><topic>Solvents</topic><topic>Temperature</topic><topic>Vegetables - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Díaz-Reinoso, Beatriz</creatorcontrib><creatorcontrib>Moure, Andrés</creatorcontrib><creatorcontrib>Domínguez, Herminia</creatorcontrib><creatorcontrib>Parajó, Juan Carlos</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of agricultural and food chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Díaz-Reinoso, Beatriz</au><au>Moure, Andrés</au><au>Domínguez, Herminia</au><au>Parajó, Juan Carlos</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Supercritical CO2 Extraction and Purification of Compounds with Antioxidant Activity</atitle><jtitle>Journal of agricultural and food chemistry</jtitle><addtitle>J. Agric. Food Chem</addtitle><date>2006-04-05</date><risdate>2006</risdate><volume>54</volume><issue>7</issue><spage>2441</spage><epage>2469</epage><pages>2441-2469</pages><issn>0021-8561</issn><eissn>1520-5118</eissn><coden>JAFCAU</coden><abstract>Supercritical fluid extraction (SCFE), based on the utilization of a fluid under supercritical conditions, is a technology suitable for extraction and purification of a variety of compounds, particularly those that have low volatility and/or are susceptible to thermal degradation. The interest in SCFE is promoted by legal limitations of conventional solvents for food and pharmaceutical uses. The physicochemical properties of supercritical CO2 (higher diffusivity, lower viscosity, and lower surface tension than conventional solvents) facilitate mass transfer and allow an environmentally friendly operation. This article presents a comprehensive compilation of data on the supercritical CO2 extraction of antioxidant compounds from vegetal materials, with particular attention to those of a phenolic nature. Aspects concerning the supercritical operation for extraction and fractionation of antioxidants compounds are considered, including equilibrium solubility of pure compounds and effects of the operational conditions on the antioxidant activity of isolated fractions. The data are compared to those reported for synthetic antioxidants and natural extracts obtained by conventional solvent extraction from vegetal matrices. Keywords: Activity; antioxidant; SCFE</abstract><cop>Washington, DC</cop><pub>American Chemical Society</pub><pmid>16569029</pmid><doi>10.1021/jf052858j</doi><tpages>29</tpages></addata></record> |
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| identifier | ISSN: 0021-8561 |
| ispartof | Journal of agricultural and food chemistry, 2006-04, Vol.54 (7), p.2441-2469 |
| issn | 0021-8561 1520-5118 |
| language | eng |
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| source | MEDLINE; American Chemical Society Journals |
| subjects | Antioxidants - isolation & purification Biological and medical sciences Chemical Phenomena Chemistry, Physical Chromatography, Supercritical Fluid - methods Food engineering Food industries Fruit - chemistry Fundamental and applied biological sciences. Psychology General aspects Hot Temperature Indicators and Reagents Plants - chemistry Pressure Solubility Solvents Temperature Vegetables - chemistry |
| title | Supercritical CO2 Extraction and Purification of Compounds with Antioxidant Activity |
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