Neonatal leptin treatment programmes leptin hypothalamic resistance and intermediary metabolic parameters in adult rats

We previously showed that neonatal leptin treatment programmes higher body weight and food intake in adult rats. Here we investigate whether leptin treatment during lactation affects the anorectic effect of leptin on adult rats and their hypothalamic leptin receptors (OB-Rb) and whether those change...

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Veröffentlicht in:	British journal of nutrition 2006-04, Vol.95 (4), p.830-837
Hauptverfasser:	Toste, F.P, Moura, E.G. de, Lisboa, P.C, Fagundes, A.T, Oliveira, E. de, Passos, M.C.F
Format:	Artikel
Sprache:	eng
Schlagworte:	adults Aging - metabolism animal models Animals Animals, Newborn appetite suppressants Biometry blood glucose Blood Glucose - metabolism blood lipids Body Composition - drug effects body mass index body weight child nutrition Drug Resistance - physiology Eating - drug effects food intake hormone receptors hypothalamic regulation Hypothalamus - metabolism infant feeding Insulin - blood lactation Lactation - physiology leptin Leptin - blood Leptin - pharmacology Male neonates nutrition-genotype interaction Rats Rats, Wistar Receptors, Cell Surface - metabolism Receptors, Leptin triacylglycerols Weight Gain - drug effects
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