Regio- and Stereoselective Route to Tetrasubstituted Olefins by the Palladium-Catalyzed Three-Component Coupling of Aryl Iodides, Internal Alkynes, and Arylboronic Acids

The Pd-catalyzed three-component coupling of readily available aryl iodides, internal alkynes, and arylboronic acids provides a convenient, one-step, regio- and stereoselective route to tetrasubstituted olefins in good to excellent yields, although electron-poor aryl iodides and dialkylalkynes norma...

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Veröffentlicht in:Journal of organic chemistry 2005-05, Vol.70 (10), p.3765-3777
Hauptverfasser: Zhou, Chengxiang, Larock, Richard C
Format: Artikel
Sprache:eng
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