The herbal medicine inchin-ko-to (TJ-135) induces apoptosis in cultured rat hepatic stellate cells

Use of herbal remedies in the treatment of various diseases has a long tradition in Eastern medicine and the liver diseases are not an exception. In their use, lack of elucidation of mechanism(s) as well as randomized, placebo-controlled clinical trials has been a problem. Recently, we and others re...

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Veröffentlicht in:	Life sciences (1973) 2006-04, Vol.78 (19), p.2226-2233
Hauptverfasser:	Ikeda, Hitoshi, Nagashima, Kayo, Yanase, Mikio, Tomiya, Tomoaki, Arai, Masahiro, Inoue, Yukiko, Tejima, Kazuaki, Nishikawa, Takako, Watanabe, Naoko, Kitamura, Kazuya, Isono, Tomomi, Yahagi, Naohisa, Noiri, Eisei, Inao, Mie, Mochida, Satoshi, Kume, Yukio, Yatomi, Yutaka, Nakahara, Kazuhiko, Omata, Masao, Fujiwara, Kenji
Format:	Artikel
Sprache:	eng
Schlagworte:	Akt Animals Apoptosis - drug effects Bad Caspase 3 Caspases - metabolism Cell Nucleus - drug effects Cell Nucleus - metabolism Cell Nucleus - pathology Cells, Cultured Cytoskeleton - drug effects Cytoskeleton - pathology Drugs, Chinese Herbal - pharmacology Enzyme-Linked Immunosorbent Assay Hepatic fibrosis Hepatocytes - cytology Hepatocytes - drug effects Hepatocytes - metabolism Immunoblotting In Situ Nick-End Labeling Male Nuclear Proteins - metabolism Rats Rats, Sprague-Dawley
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