A distributed parameter model of cerebral blood-tissue exchange with account of capillary transit time distribution

Quantitative estimates of physiological parameters associated with cerebral blood flow can be derived from the analysis of dynamic contrast-enhanced (DCE) images, using an appropriate model of the underlying tissue impulse residue function. The theoretical formulation of a distributed parameter mode...

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Veröffentlicht in:	NeuroImage (Orlando, Fla.) Fla.), 2006-04, Vol.30 (2), p.426-435
Hauptverfasser:	Koh, T.S., Cheong, L.H. Dennis, Tan, C.K. Markus, Lim, C.C. Tchoyoson
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Algorithms Blood Blood-Brain Barrier - physiology Brain Mapping Brain Neoplasms - blood supply Brain Neoplasms - pathology Brain Neoplasms - secondary Capillaries - physiology Cerebral blood flow Cerebrovascular Circulation - physiology Compartmental modeling Data Interpretation, Statistical Distributed parameter models Dynamic contrast-enhanced imaging Humans Image Processing, Computer-Assisted Male Medical imaging Microcirculation Middle Aged Models, Neurological Models, Statistical Monte Carlo Method Monte Carlo simulation Permeability Studies Tomography Tomography, X-Ray Computed Tracer kinetics modeling Tumors
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