Enhanced reactivity to vasopressin in rat basilar arteries during vasospasm after subarachnoid hemorrhage

Subarachnoid hemorrhage increases the plasma level of vasopressin, a well-known vasoconstrictor. We examined the sensitivity to vasopressin in rat basilar artery after subarachnoid hemorrhage using a rat subarachnoid hemorrhage model. Vasospasm was observed 1–2 days after subarachnoid hemorrhage ind...

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Veröffentlicht in:	European journal of pharmacology 2005-04, Vol.513 (1), p.93-100
Hauptverfasser:	Nishihashi, Tsuyoshi, Trandafir, Cristina C., Wang, Aimin, Ji, Xu, Kurahashi, Kazuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidiuretic Hormone Receptor Antagonists Basilar Artery - drug effects Basilar Artery - pathology Basilar Artery - physiopathology Biological and medical sciences Dose-Response Relationship, Drug Endothelium, Vascular - physiology Endothelium-dependent contraction In Vitro Techniques Male Medical sciences Morpholines - pharmacology Oxytocin - analogs & derivatives Oxytocin - pharmacology Pharmacology. Drug treatments Potassium Chloride - pharmacology Rat basilar artery Rats Rats, Sprague-Dawley Receptors, Vasopressin - agonists Spiro Compounds - pharmacology Subarachnoid hemorrhage Subarachnoid Hemorrhage - complications Time Factors Vasoconstriction - drug effects Vasoconstrictor Agents - pharmacology Vasopressin Vasopressin V 1 receptor Vasopressins - blood Vasopressins - pharmacology Vasospasm, Intracranial - etiology Vasospasm, Intracranial - physiopathology
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