Effects of histone deacetylase inhibitor FR901228 on the expression level of telomerase reverse transcriptase in oral cancer

We speculated whether or not the expression level of telomerase reverse transcriptase (hTERT) would be modulated by agents targeting epigenetics in oral cancer cell lines. Although hTERT is known to be targeted by epigenetic changes, it remains unclear how chemoagents targeting epigenetics work on h...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer chemotherapy and pharmacology 2005-07, Vol.56 (1), p.22-28
Hauptverfasser:	MURAKAMI, Jun, ASAUMI, Jun-Ichi, TANAKA, Noriaki, MATSUBARA, Nagahide, KISHI, Kanji, KAWAI, Noriko, TSUJIGIWA, Hidetsugu, YANAGI, Yoshinobu, NAGATSUKA, Hitoshi, INOUE, Tetsuyoshi, KOKEGUCHI, Susumu, KAWASAKI, Shoji, KURODA, Masahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics, Antineoplastic - pharmacology Antineoplastic agents Biological and medical sciences Depsipeptides - pharmacology DNA-Binding Proteins Gene Expression Profiling Histone Deacetylase Inhibitors Humans Medical sciences Mouth Neoplasms - enzymology Mouth Neoplasms - pathology Pharmacology. Drug treatments Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis Telomerase - biosynthesis Telomerase - drug effects Transcription Factors Tumor Cells, Cultured
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!