Natural History of Rising Serum Prostate-Specific Antigen in Men With Castrate Nonmetastatic Prostate Cancer

To describe the natural history of nonmetastatic prostate cancer and rising prostate-specific antigen (PSA) despite androgen deprivation therapy. The 201 patients in this report were the placebo control group from an aborted randomized controlled trial to evaluate the effects of zoledronic acid on t...

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Veröffentlicht in:	Journal of clinical oncology 2005-05, Vol.23 (13), p.2918-2925
Hauptverfasser:	SMITH, Matthew R, KABBINAVAR, Fairooz, LINNARTZ, Ronald, MING ZHENG, GOESSL, Carsten, HEI, Yong-Jiang, SMALL, Eric J, COOK, Richard, HIGANO, Celestia S, SAAD, Fred, ARIFHUSSAIN, GITTELMAN, Marc C, BILHARTZ, David L, WYNNE, Chris, MURRAY, Robin, ZINNER, Norman R, SCHULMAN, Claude
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Androgen Antagonists - therapeutic use Biological and medical sciences Biomarkers, Tumor - analysis Bone Neoplasms - prevention & control Bone Neoplasms - secondary Diphosphonates - therapeutic use Disease Progression Double-Blind Method Follow-Up Studies Humans Imidazoles - therapeutic use Male Medical sciences Nephrology. Urinary tract diseases Placebos Predictive Value of Tests Prognosis Prostate-Specific Antigen - analysis Prostatic Neoplasms - drug therapy Prostatic Neoplasms - pathology Survival Analysis Tumors Tumors of the urinary system Urinary tract. Prostate gland Zoledronic Acid
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