Overexpression of ErbB2 and ErbB3 receptors in Schwann cells of patients with Charcot-Marie-Tooth disease type 1A

Axon‐derived neuregulins (NRGs) are a family of growth factors whose binding to ErbB tyrosine kinase receptors promotes the maturation, proliferation and survival of Schwann cells (SCs). Correct NRG/ErbB signaling is essential for the homeostasis of axonal–glial complexes and seems to play a role in...

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