Oxidative Ring Cleavage in Jadomycin Biosynthesis: A Multistep Oxygenation Cascade in a Biosynthetic Black Box

Backbone‐breaking oxygenase clusters. Inactivation of the oxygenase‐encoding genes jadH and jadG and structure elucidation of novel accumulation products illustrate the essential interactions within the biosynthetic protein complex that govern the oxygenation cascade leading to the cleavage of the a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chembiochem : a European journal of chemical biology 2005-05, Vol.6 (5), p.838-845
Hauptverfasser:	Rix, Uwe, Wang, Chenchen, Chen, Yihua, Lipata, Fredilyn M, Remsing Rix, Lily L, Greenwell, Lisa M, Vining, Leo C, Yang, Keqian, Rohr, Jürgen
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence biosynthesis cleavage reactions dehydratases Flavin-Adenine Dinucleotide - metabolism Isoquinolines - chemistry Isoquinolines - metabolism Magnetic Resonance Spectroscopy Molecular Sequence Data Molecular Structure Multigene Family NADP - metabolism Naphthoquinones - chemistry Naphthoquinones - metabolism Oxidation-Reduction oxygenases Oxygenases - chemistry Oxygenases - metabolism polyketides Protein Binding proteins Sequence Alignment Streptomyces - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!