Monitoring glycosylation pattern changes of glycoproteins using multi-lectin affinity chromatography

Previously, we reported that the distribution of glycoproteins into the lectin displacement fractions of a multi-lectin affinity column was determined by the glycosylation patterns of the proteins. This distribution was observed by the sequential use of displacers specific to the lectins in the colu...

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Veröffentlicht in:	Journal of Chromatography A 2005-04, Vol.1070 (1), p.57-64
Hauptverfasser:	Yang, Ziping, Hancock, William S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analytical, structural and metabolic biochemistry Biological and medical sciences Chromatography, Liquid - methods Fucose Fucosidase Fundamental and applied biological sciences. Psychology Glycoproteins Glycoproteins - blood Glycoproteins - chemistry Glycoproteome Glycosylation Glycosylation pattern change Human serum Humans Isoelectric Focusing Lectin Lectins - chemistry Mass Spectrometry Molecular Sequence Data Neuraminidase Proteins Sensitivity and Specificity Sialic acid Transferrin
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