Genotyping of human neutrophil antigen-5a (Ond)

Antibodies to human neutrophil alloantigens (HNA) can cause immune‐mediated neutropenias and transfusion complications. The diagnosis of antibodies to the HNA‐5a (Ond) isoform of the αLβ2 integrin is hampered by the lack of reliable methods for HNA‐5a antigen typing. We have devised a polymerase cha...

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Veröffentlicht in:	Transfusion medicine (Oxford, England) England), 2005-04, Vol.15 (2), p.115-117
Hauptverfasser:	Sachs, U. J. H., Reil, A., Bauer, C., Bux, J., Bein, G., Santoso, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Continental Population Groups Gene Frequency - genetics Genotype granulocyte serology human neutrophil antigen-5a/Ond Humans Isoantigens - genetics Isoantigens - immunology molecular diagnosis Neutrophils - immunology PCR-SSP Polymerase Chain Reaction - methods Polymorphism, Single-Stranded Conformational
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