Striatal expression of GDNF and differential vulnerability of midbrain dopaminergic cells

Glial cell line‐derived neurotrophic factor (GDNF) is a member of the transforming growth factor‐β superfamily that when exogenously administrated exerts a potent trophic action on dopaminergic (DA) cells. Although we know a lot about its signalling mechanisms and pharmacological effects, physiologi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The European journal of neuroscience 2005-04, Vol.21 (7), p.1815-1827
Hauptverfasser:	Barroso-Chinea, Pedro, Cruz-Muros, Ignacio, Aymerich, María S., Rodríguez-Díaz, Manuel, Afonso-Oramas, Domingo, Lanciego, José L., González-Hernández, Tomás
Format:	Artikel
Sprache:	eng
Schlagworte:	6-OHDA Analysis of Variance Animals Cell Count - methods Colchicine - pharmacology Corpus Striatum - metabolism Dopamine - metabolism Gene Expression Regulation - drug effects Gene Expression Regulation - physiology Glial Cell Line-Derived Neurotrophic Factor Glial Cell Line-Derived Neurotrophic Factor Receptors Immunohistochemistry - methods In Situ Hybridization - methods Male Mesencephalon - cytology Nerve Growth Factors - metabolism Neural Networks (Computer) Neurons - metabolism neuroprotection Parkinson's disease Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins c-ret rat Rats Rats, Sprague-Dawley Receptor Protein-Tyrosine Kinases - genetics Receptor Protein-Tyrosine Kinases - metabolism Reverse Transcriptase Polymerase Chain Reaction - methods RNA, Messenger - biosynthesis Stilbamidines - metabolism substantia nigra Tyrosine 3-Monooxygenase - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!