Intra-arterial thrombolytic therapy in peri-coronary angiography ischemic stroke
Intra-arterial thrombolysis (IAT) for peri-coronary angiography (CA) stroke may be safe and efficacious. However, IAT may increase the risk of intracranial hemorrhage (ICH). A retrospective study was performed involving 3 university hospitals. All peri-CA IAT-treated cases were identified. Patient d...
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| Veröffentlicht in: | Stroke (1970) 2005-05, Vol.36 (5), p.1083-1084 |
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| container_title | Stroke (1970) |
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| creator | ZAIDAT, Osama O SLIVKA, Andy P MOHAMMAD, Yousef GRAFFAGNINO, Carmelo SMITH, Tony P ENTERLINE, David S CHRISTOFORIDIS, Greg A ALEXANDER, Michael J LANDIS, Dennis M. D SUAREZ, Jose I |
| description | Intra-arterial thrombolysis (IAT) for peri-coronary angiography (CA) stroke may be safe and efficacious. However, IAT may increase the risk of intracranial hemorrhage (ICH).
A retrospective study was performed involving 3 university hospitals. All peri-CA IAT-treated cases were identified. Patient demographics, stroke severity, angiographic findings, thrombolytic use, modified Rankin Scale (mRS), ICH, and mortality were determined.
A total of 21 patients with post-left CA stroke were treated with IAT (mean age 71.8+/-12.3 years). Arterial occlusion was found in 14 (66.7%) and 7 (33.3%) of the anterior and posterior circulation, respectively. Mean time-to-therapy was 36+/-12 minutes from the time the neurological deficit was noted. mRS < or =2 occurred in 10 of 21 (48%) patients. Patients with younger age and shorter time-to-IAT had more complete arterial recanalization and clinical recovery. Symptomatic ICH occurred in 3 (14%) cases, and 4 (19%) patients died.
Peri-CA IAT appears to be feasible and safe without increased risk of symptomatic ICH and death when compared with the previously reported IAT literature. |
| doi_str_mv | 10.1161/01.STR.0000162392.44326.ec |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67786128</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>19764803</sourcerecordid><originalsourceid>FETCH-LOGICAL-c532t-b7ed40cd2a6cdc9a74cbabd2efd65bdae4e742c48f16d1666a587204296b751e3</originalsourceid><addsrcrecordid>eNqFkMtOwzAQRS0EoqXwC6hCgl2CXxkn7BDiJVUCQVlbjjNpA0lc7HTRv8fQSl3izci6Z2bsQ8gFoyljwK4pS9_nbymNhwEXBU-lFBxStAdkzDIuEwk8PyRjSkWRcFkUI3ISwmfkucizYzJiWU45CBiT1-d-8CYxfkDfmHY6LL3rStduhsbGC3qz2kybfrqKcWKdd73xm6npF41bxGwZw2CX2EU6DN594Sk5qk0b8GxXJ-Tj4X5-95TMXh6f725nic0EH5JSYSWprbgBW9nCKGlLU1Yc6wqysjIoUUluZV4zqBgAmCxXnEpeQKkyhmJCrrZzV959rzEMuosvwbY1Pbp10KBUDozn_4KsUCBzKiJ4swWtdyF4rPXKN138rmZU_4rXlOkoXu_F6z_xGm1sPt9tWZcdVvvWnekIXO4AE6xpa29624Q9ByoDJUH8AFWJjqk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>19764803</pqid></control><display><type>article</type><title>Intra-arterial thrombolytic therapy in peri-coronary angiography ischemic stroke</title><source>Journals@Ovid Ovid Autoload</source><source>MEDLINE</source><source>American Heart Association Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>ZAIDAT, Osama O ; SLIVKA, Andy P ; MOHAMMAD, Yousef ; GRAFFAGNINO, Carmelo ; SMITH, Tony P ; ENTERLINE, David S ; CHRISTOFORIDIS, Greg A ; ALEXANDER, Michael J ; LANDIS, Dennis M. D ; SUAREZ, Jose I</creator><creatorcontrib>ZAIDAT, Osama O ; SLIVKA, Andy P ; MOHAMMAD, Yousef ; GRAFFAGNINO, Carmelo ; SMITH, Tony P ; ENTERLINE, David S ; CHRISTOFORIDIS, Greg A ; ALEXANDER, Michael J ; LANDIS, Dennis M. D ; SUAREZ, Jose I</creatorcontrib><description>Intra-arterial thrombolysis (IAT) for peri-coronary angiography (CA) stroke may be safe and efficacious. However, IAT may increase the risk of intracranial hemorrhage (ICH).
A retrospective study was performed involving 3 university hospitals. All peri-CA IAT-treated cases were identified. Patient demographics, stroke severity, angiographic findings, thrombolytic use, modified Rankin Scale (mRS), ICH, and mortality were determined.
A total of 21 patients with post-left CA stroke were treated with IAT (mean age 71.8+/-12.3 years). Arterial occlusion was found in 14 (66.7%) and 7 (33.3%) of the anterior and posterior circulation, respectively. Mean time-to-therapy was 36+/-12 minutes from the time the neurological deficit was noted. mRS < or =2 occurred in 10 of 21 (48%) patients. Patients with younger age and shorter time-to-IAT had more complete arterial recanalization and clinical recovery. Symptomatic ICH occurred in 3 (14%) cases, and 4 (19%) patients died.
Peri-CA IAT appears to be feasible and safe without increased risk of symptomatic ICH and death when compared with the previously reported IAT literature.</description><identifier>ISSN: 0039-2499</identifier><identifier>EISSN: 1524-4628</identifier><identifier>DOI: 10.1161/01.STR.0000162392.44326.ec</identifier><identifier>PMID: 15802636</identifier><identifier>CODEN: SJCCA7</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Aged ; Biological and medical sciences ; Blood. Blood coagulation. Reticuloendothelial system ; Brain Ischemia - drug therapy ; Brain Ischemia - etiology ; Cardiac Catheterization - adverse effects ; Coronary Angiography - adverse effects ; Female ; Fibrinolytic Agents - administration & dosage ; Fibrinolytic Agents - therapeutic use ; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy ; Humans ; Infusions, Intra-Arterial ; Male ; Medical sciences ; Nervous system (semeiology, syndromes) ; Neurology ; Pharmacology. Drug treatments ; Retrospective Studies ; Stroke - drug therapy ; Stroke - etiology ; Thrombolytic Therapy ; Treatment Outcome ; Vascular diseases and vascular malformations of the nervous system</subject><ispartof>Stroke (1970), 2005-05, Vol.36 (5), p.1083-1084</ispartof><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c532t-b7ed40cd2a6cdc9a74cbabd2efd65bdae4e742c48f16d1666a587204296b751e3</citedby><cites>FETCH-LOGICAL-c532t-b7ed40cd2a6cdc9a74cbabd2efd65bdae4e742c48f16d1666a587204296b751e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,3674,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16756746$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15802636$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ZAIDAT, Osama O</creatorcontrib><creatorcontrib>SLIVKA, Andy P</creatorcontrib><creatorcontrib>MOHAMMAD, Yousef</creatorcontrib><creatorcontrib>GRAFFAGNINO, Carmelo</creatorcontrib><creatorcontrib>SMITH, Tony P</creatorcontrib><creatorcontrib>ENTERLINE, David S</creatorcontrib><creatorcontrib>CHRISTOFORIDIS, Greg A</creatorcontrib><creatorcontrib>ALEXANDER, Michael J</creatorcontrib><creatorcontrib>LANDIS, Dennis M. D</creatorcontrib><creatorcontrib>SUAREZ, Jose I</creatorcontrib><title>Intra-arterial thrombolytic therapy in peri-coronary angiography ischemic stroke</title><title>Stroke (1970)</title><addtitle>Stroke</addtitle><description>Intra-arterial thrombolysis (IAT) for peri-coronary angiography (CA) stroke may be safe and efficacious. However, IAT may increase the risk of intracranial hemorrhage (ICH).
A retrospective study was performed involving 3 university hospitals. All peri-CA IAT-treated cases were identified. Patient demographics, stroke severity, angiographic findings, thrombolytic use, modified Rankin Scale (mRS), ICH, and mortality were determined.
A total of 21 patients with post-left CA stroke were treated with IAT (mean age 71.8+/-12.3 years). Arterial occlusion was found in 14 (66.7%) and 7 (33.3%) of the anterior and posterior circulation, respectively. Mean time-to-therapy was 36+/-12 minutes from the time the neurological deficit was noted. mRS < or =2 occurred in 10 of 21 (48%) patients. Patients with younger age and shorter time-to-IAT had more complete arterial recanalization and clinical recovery. Symptomatic ICH occurred in 3 (14%) cases, and 4 (19%) patients died.
Peri-CA IAT appears to be feasible and safe without increased risk of symptomatic ICH and death when compared with the previously reported IAT literature.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Blood. Blood coagulation. Reticuloendothelial system</subject><subject>Brain Ischemia - drug therapy</subject><subject>Brain Ischemia - etiology</subject><subject>Cardiac Catheterization - adverse effects</subject><subject>Coronary Angiography - adverse effects</subject><subject>Female</subject><subject>Fibrinolytic Agents - administration & dosage</subject><subject>Fibrinolytic Agents - therapeutic use</subject><subject>Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy</subject><subject>Humans</subject><subject>Infusions, Intra-Arterial</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Pharmacology. Drug treatments</subject><subject>Retrospective Studies</subject><subject>Stroke - drug therapy</subject><subject>Stroke - etiology</subject><subject>Thrombolytic Therapy</subject><subject>Treatment Outcome</subject><subject>Vascular diseases and vascular malformations of the nervous system</subject><issn>0039-2499</issn><issn>1524-4628</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtOwzAQRS0EoqXwC6hCgl2CXxkn7BDiJVUCQVlbjjNpA0lc7HTRv8fQSl3izci6Z2bsQ8gFoyljwK4pS9_nbymNhwEXBU-lFBxStAdkzDIuEwk8PyRjSkWRcFkUI3ISwmfkucizYzJiWU45CBiT1-d-8CYxfkDfmHY6LL3rStduhsbGC3qz2kybfrqKcWKdd73xm6npF41bxGwZw2CX2EU6DN594Sk5qk0b8GxXJ-Tj4X5-95TMXh6f725nic0EH5JSYSWprbgBW9nCKGlLU1Yc6wqysjIoUUluZV4zqBgAmCxXnEpeQKkyhmJCrrZzV959rzEMuosvwbY1Pbp10KBUDozn_4KsUCBzKiJ4swWtdyF4rPXKN138rmZU_4rXlOkoXu_F6z_xGm1sPt9tWZcdVvvWnekIXO4AE6xpa29624Q9ByoDJUH8AFWJjqk</recordid><startdate>20050501</startdate><enddate>20050501</enddate><creator>ZAIDAT, Osama O</creator><creator>SLIVKA, Andy P</creator><creator>MOHAMMAD, Yousef</creator><creator>GRAFFAGNINO, Carmelo</creator><creator>SMITH, Tony P</creator><creator>ENTERLINE, David S</creator><creator>CHRISTOFORIDIS, Greg A</creator><creator>ALEXANDER, Michael J</creator><creator>LANDIS, Dennis M. D</creator><creator>SUAREZ, Jose I</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>20050501</creationdate><title>Intra-arterial thrombolytic therapy in peri-coronary angiography ischemic stroke</title><author>ZAIDAT, Osama O ; SLIVKA, Andy P ; MOHAMMAD, Yousef ; GRAFFAGNINO, Carmelo ; SMITH, Tony P ; ENTERLINE, David S ; CHRISTOFORIDIS, Greg A ; ALEXANDER, Michael J ; LANDIS, Dennis M. D ; SUAREZ, Jose I</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c532t-b7ed40cd2a6cdc9a74cbabd2efd65bdae4e742c48f16d1666a587204296b751e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Blood. Blood coagulation. Reticuloendothelial system</topic><topic>Brain Ischemia - drug therapy</topic><topic>Brain Ischemia - etiology</topic><topic>Cardiac Catheterization - adverse effects</topic><topic>Coronary Angiography - adverse effects</topic><topic>Female</topic><topic>Fibrinolytic Agents - administration & dosage</topic><topic>Fibrinolytic Agents - therapeutic use</topic><topic>Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy</topic><topic>Humans</topic><topic>Infusions, Intra-Arterial</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Pharmacology. Drug treatments</topic><topic>Retrospective Studies</topic><topic>Stroke - drug therapy</topic><topic>Stroke - etiology</topic><topic>Thrombolytic Therapy</topic><topic>Treatment Outcome</topic><topic>Vascular diseases and vascular malformations of the nervous system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ZAIDAT, Osama O</creatorcontrib><creatorcontrib>SLIVKA, Andy P</creatorcontrib><creatorcontrib>MOHAMMAD, Yousef</creatorcontrib><creatorcontrib>GRAFFAGNINO, Carmelo</creatorcontrib><creatorcontrib>SMITH, Tony P</creatorcontrib><creatorcontrib>ENTERLINE, David S</creatorcontrib><creatorcontrib>CHRISTOFORIDIS, Greg A</creatorcontrib><creatorcontrib>ALEXANDER, Michael J</creatorcontrib><creatorcontrib>LANDIS, Dennis M. D</creatorcontrib><creatorcontrib>SUAREZ, Jose I</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Stroke (1970)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ZAIDAT, Osama O</au><au>SLIVKA, Andy P</au><au>MOHAMMAD, Yousef</au><au>GRAFFAGNINO, Carmelo</au><au>SMITH, Tony P</au><au>ENTERLINE, David S</au><au>CHRISTOFORIDIS, Greg A</au><au>ALEXANDER, Michael J</au><au>LANDIS, Dennis M. D</au><au>SUAREZ, Jose I</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intra-arterial thrombolytic therapy in peri-coronary angiography ischemic stroke</atitle><jtitle>Stroke (1970)</jtitle><addtitle>Stroke</addtitle><date>2005-05-01</date><risdate>2005</risdate><volume>36</volume><issue>5</issue><spage>1083</spage><epage>1084</epage><pages>1083-1084</pages><issn>0039-2499</issn><eissn>1524-4628</eissn><coden>SJCCA7</coden><abstract>Intra-arterial thrombolysis (IAT) for peri-coronary angiography (CA) stroke may be safe and efficacious. However, IAT may increase the risk of intracranial hemorrhage (ICH).
A retrospective study was performed involving 3 university hospitals. All peri-CA IAT-treated cases were identified. Patient demographics, stroke severity, angiographic findings, thrombolytic use, modified Rankin Scale (mRS), ICH, and mortality were determined.
A total of 21 patients with post-left CA stroke were treated with IAT (mean age 71.8+/-12.3 years). Arterial occlusion was found in 14 (66.7%) and 7 (33.3%) of the anterior and posterior circulation, respectively. Mean time-to-therapy was 36+/-12 minutes from the time the neurological deficit was noted. mRS < or =2 occurred in 10 of 21 (48%) patients. Patients with younger age and shorter time-to-IAT had more complete arterial recanalization and clinical recovery. Symptomatic ICH occurred in 3 (14%) cases, and 4 (19%) patients died.
Peri-CA IAT appears to be feasible and safe without increased risk of symptomatic ICH and death when compared with the previously reported IAT literature.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>15802636</pmid><doi>10.1161/01.STR.0000162392.44326.ec</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Stroke (1970), 2005-05, Vol.36 (5), p.1083-1084 |
| issn | 0039-2499 1524-4628 |
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| source | Journals@Ovid Ovid Autoload; MEDLINE; American Heart Association Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Aged Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Brain Ischemia - drug therapy Brain Ischemia - etiology Cardiac Catheterization - adverse effects Coronary Angiography - adverse effects Female Fibrinolytic Agents - administration & dosage Fibrinolytic Agents - therapeutic use Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Infusions, Intra-Arterial Male Medical sciences Nervous system (semeiology, syndromes) Neurology Pharmacology. Drug treatments Retrospective Studies Stroke - drug therapy Stroke - etiology Thrombolytic Therapy Treatment Outcome Vascular diseases and vascular malformations of the nervous system |
| title | Intra-arterial thrombolytic therapy in peri-coronary angiography ischemic stroke |
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