Symptoms of gastro‐oesophageal reflux disease and the severity of obstructive sleep apnoea syndrome are not related in sleep disorders center patients

Summary Background : Studies suggest obstructive sleep apnea syndrome (OSAS) frequently manifests in patients with gastroesophageal reflux disease (GERD) and that there may be a causal relationship. Aim : To determine the relationship between OSAS and symptoms of GERD. Methods : Consecutive patients...

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Veröffentlicht in:Alimentary pharmacology & therapeutics 2005-05, Vol.21 (9), p.1127-1133
Hauptverfasser: Kim, H.‐N., Vorona, R. D., Winn, M. P., Doviak, M., Johnson, D. A., Catesby Ware, J.
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container_end_page 1133
container_issue 9
container_start_page 1127
container_title Alimentary pharmacology & therapeutics
container_volume 21
creator Kim, H.‐N.
Vorona, R. D.
Winn, M. P.
Doviak, M.
Johnson, D. A.
Catesby Ware, J.
description Summary Background : Studies suggest obstructive sleep apnea syndrome (OSAS) frequently manifests in patients with gastroesophageal reflux disease (GERD) and that there may be a causal relationship. Aim : To determine the relationship between OSAS and symptoms of GERD. Methods : Consecutive patients referred to the Sleep Disorders Center (SDC) 18 years and older with polysomnographically defined OSAS were evaluated prospectively for GERD using a validated symptoms questionnaire. The GERD and OSAS relationship was assessed by 1) determining frequency of GERD in patients with and without OSAS; 2) ascertaining the relationship between OSAS severity categories and presence of GERD; 3) examining GERD score in relation to those factors that might affect both GERD and OSAS, e.g. obesity. Results : One thousand and twenty‐three SDC patients met entry citeria. Amongst participants, GERD was common (29% of women and 17% of males) and OSAS extremely common (58% of women and 80% of males). GERD score did not correlate with OSAS variables. The severity of OSAS did not influence the prevalence of GERD. Conclusion : In a large group of patients referred to a sleep disorders center, there was no relationship between OSAS and GERD symptoms. Also, there was no relationship between the severity of OSAS and the likelihood of GERD symptoms.
doi_str_mv 10.1111/j.1365-2036.2005.02447.x
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D. ; Winn, M. P. ; Doviak, M. ; Johnson, D. A. ; Catesby Ware, J.</creator><creatorcontrib>Kim, H.‐N. ; Vorona, R. D. ; Winn, M. P. ; Doviak, M. ; Johnson, D. A. ; Catesby Ware, J.</creatorcontrib><description>Summary Background : Studies suggest obstructive sleep apnea syndrome (OSAS) frequently manifests in patients with gastroesophageal reflux disease (GERD) and that there may be a causal relationship. Aim : To determine the relationship between OSAS and symptoms of GERD. Methods : Consecutive patients referred to the Sleep Disorders Center (SDC) 18 years and older with polysomnographically defined OSAS were evaluated prospectively for GERD using a validated symptoms questionnaire. The GERD and OSAS relationship was assessed by 1) determining frequency of GERD in patients with and without OSAS; 2) ascertaining the relationship between OSAS severity categories and presence of GERD; 3) examining GERD score in relation to those factors that might affect both GERD and OSAS, e.g. obesity. Results : One thousand and twenty‐three SDC patients met entry citeria. Amongst participants, GERD was common (29% of women and 17% of males) and OSAS extremely common (58% of women and 80% of males). GERD score did not correlate with OSAS variables. The severity of OSAS did not influence the prevalence of GERD. Conclusion : In a large group of patients referred to a sleep disorders center, there was no relationship between OSAS and GERD symptoms. Also, there was no relationship between the severity of OSAS and the likelihood of GERD symptoms.</description><identifier>ISSN: 0269-2813</identifier><identifier>EISSN: 1365-2036</identifier><identifier>DOI: 10.1111/j.1365-2036.2005.02447.x</identifier><identifier>PMID: 15854175</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Ltd</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Body Mass Index ; Digestive system ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Gastroesophageal Reflux - complications ; Humans ; Male ; Medical sciences ; Middle Aged ; Pharmacology. 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D.</creatorcontrib><creatorcontrib>Winn, M. P.</creatorcontrib><creatorcontrib>Doviak, M.</creatorcontrib><creatorcontrib>Johnson, D. A.</creatorcontrib><creatorcontrib>Catesby Ware, J.</creatorcontrib><title>Symptoms of gastro‐oesophageal reflux disease and the severity of obstructive sleep apnoea syndrome are not related in sleep disorders center patients</title><title>Alimentary pharmacology &amp; therapeutics</title><addtitle>Aliment Pharmacol Ther</addtitle><description>Summary Background : Studies suggest obstructive sleep apnea syndrome (OSAS) frequently manifests in patients with gastroesophageal reflux disease (GERD) and that there may be a causal relationship. Aim : To determine the relationship between OSAS and symptoms of GERD. Methods : Consecutive patients referred to the Sleep Disorders Center (SDC) 18 years and older with polysomnographically defined OSAS were evaluated prospectively for GERD using a validated symptoms questionnaire. The GERD and OSAS relationship was assessed by 1) determining frequency of GERD in patients with and without OSAS; 2) ascertaining the relationship between OSAS severity categories and presence of GERD; 3) examining GERD score in relation to those factors that might affect both GERD and OSAS, e.g. obesity. Results : One thousand and twenty‐three SDC patients met entry citeria. Amongst participants, GERD was common (29% of women and 17% of males) and OSAS extremely common (58% of women and 80% of males). GERD score did not correlate with OSAS variables. The severity of OSAS did not influence the prevalence of GERD. Conclusion : In a large group of patients referred to a sleep disorders center, there was no relationship between OSAS and GERD symptoms. 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D.</creatorcontrib><creatorcontrib>Winn, M. P.</creatorcontrib><creatorcontrib>Doviak, M.</creatorcontrib><creatorcontrib>Johnson, D. A.</creatorcontrib><creatorcontrib>Catesby Ware, J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Alimentary pharmacology &amp; therapeutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, H.‐N.</au><au>Vorona, R. D.</au><au>Winn, M. P.</au><au>Doviak, M.</au><au>Johnson, D. A.</au><au>Catesby Ware, J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Symptoms of gastro‐oesophageal reflux disease and the severity of obstructive sleep apnoea syndrome are not related in sleep disorders center patients</atitle><jtitle>Alimentary pharmacology &amp; therapeutics</jtitle><addtitle>Aliment Pharmacol Ther</addtitle><date>2005-05</date><risdate>2005</risdate><volume>21</volume><issue>9</issue><spage>1127</spage><epage>1133</epage><pages>1127-1133</pages><issn>0269-2813</issn><eissn>1365-2036</eissn><abstract>Summary Background : Studies suggest obstructive sleep apnea syndrome (OSAS) frequently manifests in patients with gastroesophageal reflux disease (GERD) and that there may be a causal relationship. Aim : To determine the relationship between OSAS and symptoms of GERD. 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subjects Adult
Aged
Biological and medical sciences
Body Mass Index
Digestive system
Female
Gastroenterology. Liver. Pancreas. Abdomen
Gastroesophageal Reflux - complications
Humans
Male
Medical sciences
Middle Aged
Pharmacology. Drug treatments
Polysomnography
Referral and Consultation
Sleep Apnea, Obstructive - complications
title Symptoms of gastro‐oesophageal reflux disease and the severity of obstructive sleep apnoea syndrome are not related in sleep disorders center patients
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