Endophytic fungal metabolite fumigaclavine C causes relaxation of isolated rat aortic rings

Abstract Two indole alkaloids were isolated from the culture of ASPERGILLUS FUMIGATUS (strain No. CY018), an endophytic fungus harboring inside the elder leaf of CYNODON DACTYLON. These two chemicals were identified as fumigaclavine C and fumitremorgin C. In screening the bioactivity of these two in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Planta medica 2006-04, Vol.72 (5), p.387-392
Hauptverfasser:	Ma, H.Y, Song, Y.C, Mao, Y.Y, Jiang, J.H, Tan, R.X, Luo, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals aorta Aorta, Thoracic - drug effects Aspergillus fumigatus Aspergillus fumigatus - isolation & purification Aspergillus fumigatus - metabolism Biological and medical sciences calcium channels chemical structure Cynodon - microbiology Cynodon dactylon dose response Dose-Response Relationship, Drug endophytes Ergot Alkaloids fumigaclavine fumitremorgin General pharmacology human health indole alkaloids Indole Alkaloids - pharmacology Male Medical sciences muscle relaxants Muscle, Smooth, Vascular - drug effects Original Paper Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Leaves - microbiology potassium channels Rats Rats, Sprague-Dawley secondary metabolites signal transduction smooth muscle vasodilation Vasodilation - drug effects vasodilator agents Vasodilator Agents - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!