Clinical review: Healing in gastrointestinal anastomoses, Part I
Gastrointestinal healing is a topic rarely reviewed in the literature, yet it is of paramount importance to the surgeon. Failure of anastomotic healing may lead to life‐threatening complications, additional surgical procedures, increased length of stay, increased cost, long‐term disability, and redu...
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Veröffentlicht in: | Microsurgery 2006, Vol.26 (3), p.131-136 |
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creator | Thompson, Sarah K. Chang, Eugene Y. Jobe, Blair A. |
description | Gastrointestinal healing is a topic rarely reviewed in the literature, yet it is of paramount importance to the surgeon. Failure of anastomotic healing may lead to life‐threatening complications, additional surgical procedures, increased length of stay, increased cost, long‐term disability, and reduced quality of life for the patient. The goal of this article is to review the biological response to wounded tissue, to outline discrete differences between skin and gastrointestinal healing, to discuss local and systemic factors important to gastrointestinal healing, and to compare methods of measuring collagen content and strength of the newly formed anastomosis. Part II of this review will focus on techniques and therapies available to optimize anastomotic healing. © 2006 Wiley‐Liss, Inc. Microsurgery, 2006. |
doi_str_mv | 10.1002/micr.20197 |
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Failure of anastomotic healing may lead to life‐threatening complications, additional surgical procedures, increased length of stay, increased cost, long‐term disability, and reduced quality of life for the patient. The goal of this article is to review the biological response to wounded tissue, to outline discrete differences between skin and gastrointestinal healing, to discuss local and systemic factors important to gastrointestinal healing, and to compare methods of measuring collagen content and strength of the newly formed anastomosis. Part II of this review will focus on techniques and therapies available to optimize anastomotic healing. © 2006 Wiley‐Liss, Inc. 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Failure of anastomotic healing may lead to life‐threatening complications, additional surgical procedures, increased length of stay, increased cost, long‐term disability, and reduced quality of life for the patient. The goal of this article is to review the biological response to wounded tissue, to outline discrete differences between skin and gastrointestinal healing, to discuss local and systemic factors important to gastrointestinal healing, and to compare methods of measuring collagen content and strength of the newly formed anastomosis. Part II of this review will focus on techniques and therapies available to optimize anastomotic healing. © 2006 Wiley‐Liss, Inc. Microsurgery, 2006.</description><subject>Anastomosis, Surgical</subject><subject>Biological and medical sciences</subject><subject>Collagen - analysis</subject><subject>Gastrointestinal Diseases - surgery</subject><subject>Gastrointestinal Tract - anatomy & histology</subject><subject>General aspects</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. 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Graft diseases</topic><topic>Tensile Strength</topic><topic>Wound Healing - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thompson, Sarah K.</creatorcontrib><creatorcontrib>Chang, Eugene Y.</creatorcontrib><creatorcontrib>Jobe, Blair A.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Microsurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thompson, Sarah K.</au><au>Chang, Eugene Y.</au><au>Jobe, Blair A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical review: Healing in gastrointestinal anastomoses, Part I</atitle><jtitle>Microsurgery</jtitle><addtitle>Microsurgery</addtitle><date>2006</date><risdate>2006</risdate><volume>26</volume><issue>3</issue><spage>131</spage><epage>136</epage><pages>131-136</pages><issn>0738-1085</issn><eissn>1098-2752</eissn><coden>MSRGDQ</coden><abstract>Gastrointestinal healing is a topic rarely reviewed in the literature, yet it is of paramount importance to the surgeon. Failure of anastomotic healing may lead to life‐threatening complications, additional surgical procedures, increased length of stay, increased cost, long‐term disability, and reduced quality of life for the patient. The goal of this article is to review the biological response to wounded tissue, to outline discrete differences between skin and gastrointestinal healing, to discuss local and systemic factors important to gastrointestinal healing, and to compare methods of measuring collagen content and strength of the newly formed anastomosis. Part II of this review will focus on techniques and therapies available to optimize anastomotic healing. © 2006 Wiley‐Liss, Inc. Microsurgery, 2006.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>16518804</pmid><doi>10.1002/micr.20197</doi><tpages>6</tpages></addata></record> |
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subjects | Anastomosis, Surgical Biological and medical sciences Collagen - analysis Gastrointestinal Diseases - surgery Gastrointestinal Tract - anatomy & histology General aspects Humans Medical sciences Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tensile Strength Wound Healing - physiology |
title | Clinical review: Healing in gastrointestinal anastomoses, Part I |
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