A Direct Signaling Role for Phosphatidylinositol 4,5-Bisphosphate (PIP2) in the Visual Excitation Process of Microvillar Receptors

In microvillar photoreceptors the pivotal role of phospholipase C in light transduction is undisputed, but previous attempts to account for the photoresponse solely in terms of downstream products of phosphatidylinositol 4,5-bisphosphate (PIP2) hydrolysis have proved wanting. In other systems PIP2 h...

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Veröffentlicht in:	The Journal of biological chemistry 2005-04, Vol.280 (17), p.16784-16789
Hauptverfasser:	del Pilar Gomez, Maria, Nasi, Enrico
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Diglycerides - metabolism Electrophysiology Hydrolysis Inositol 1,4,5-Trisphosphate - metabolism Light Microvilli - metabolism Mollusca Phosphatidylinositol 4,5-Diphosphate - physiology Potassium - metabolism Signal Transduction Type C Phospholipases - metabolism Vision, Ocular
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