Therapeutic potential of the SARMs: revisiting the androgen receptor for drug discovery

Selective androgen receptor modulators (SARMS) bind to the androgen receptor and demonstrate anabolic activity in a variety of tissues; however, unlike testosterone and other anabolic steroids, these nonsteroidal agents are able to induce bone and muscle growth, as well as shrinking the prostate. Th...

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Veröffentlicht in:	Expert opinion on investigational drugs 2006-04, Vol.15 (4), p.377-387
Hauptverfasser:	Segal, Scott, Narayanan, Ramesh, Dalton, James T
Format:	Artikel
Sprache:	eng
Schlagworte:	androgen Androgen Antagonists - pharmacology Androgen Antagonists - therapeutic use Androgen Receptor Antagonists Androgens - pharmacology Androgens - therapeutic use Animals Drug Design Humans hypogonadism Male muscle wasting osteoporosis Receptors, Androgen - metabolism steroid
Online-Zugang:	Volltext
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