Conjugated linoleic acid suppresses the secretion of atherogenic lipoproteins from human HepG2 liver cells

Studies in healthy humans have shown that consumption of conjugated linoleic acid (CLA) significantly reduced very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) blood concentrations. We propose that decreased concentrations are due to the inhibition of VLDL production and secretio...

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Veröffentlicht in:	Clinical chemistry and laboratory medicine 2005-01, Vol.43 (3), p.269-274
Hauptverfasser:	Pal, Sebely, Takechi, Ryusuke, Ho, Suleen S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apolipoprotein B-100 apolipoprotein B100 (apoB100) Apolipoproteins B - drug effects Apolipoproteins B - metabolism atherosclerosis Biological and medical sciences Cell Line Cells, Cultured cholesterol Cholesterol - metabolism Cholesterol Esters - metabolism conjugated linoleic acid General aspects Hepatocytes - drug effects Hepatocytes - metabolism Hepatocytes - secretion HepG2 liver cells Humans Investigative techniques, diagnostic techniques (general aspects) Linoleic Acids - pharmacology Linoleic Acids, Conjugated - pharmacology lipoprotein Lipoproteins, LDL - blood Lipoproteins, LDL - drug effects Lipoproteins, LDL - metabolism Lipoproteins, LDL - secretion Lipoproteins, VLDL - drug effects Lipoproteins, VLDL - metabolism Lipoproteins, VLDL - secretion Medical sciences Palmitic Acid - pharmacology
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