Overview of the Epidemiological Profile and Laboratory Detection of Extended-Spectrum β-Lactamases

Extended-spectrum β-lactamases (ESBLs) are plasmid-mediated bacterial enzymes that confer resistance to a broad range of β-lactams. They are descended by genetic mutation from native β-lactamases found in gram-negative bacteria, especially infectious strains of Escherichia coli and Klebsiella specie...

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Veröffentlicht in:	Clinical infectious diseases 2006-04, Vol.42, p.S153-S163
Hauptverfasser:	Pfaller, Michael A., John Segreti
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Antimicrobials Bacteria beta-Lactam Resistance - genetics beta-Lactamases - classification beta-Lactamases - genetics beta-Lactamases - isolation & purification Cephalosporins Enterobacteriaceae Enterobacteriaceae - drug effects Enterobacteriaceae - enzymology Enterobacteriaceae - genetics Enterobacteriaceae Infections - drug therapy Enterobacteriaceae Infections - epidemiology Enterobacteriaceae Infections - microbiology Enzymes Escherichia coli Escherichia coli - drug effects Escherichia coli - enzymology Escherichia coli - genetics Escherichia coli Infections - classification Escherichia coli Infections - epidemiology Escherichia coli Infections - microbiology Humans Infections Klebsiella Klebsiella - drug effects Klebsiella - enzymology Klebsiella - genetics Klebsiella Infections - classification Klebsiella Infections - epidemiology Klebsiella Infections - microbiology Microbial Sensitivity Tests - methods Microbial Sensitivity Tests - standards Phenotypes Predisposing factors Risk Factors
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