Interfering with hepatitis C virus IRES activity using RNA molecules identified by a novel in vitro selection method

Hepatitis C virus (HCV) infection is one of the world's major health problems, and the identification of efficient HCV inhibitors is a major goal. Here we report the isolation of efficient anti-HCV internal ribosome entry site (IRES) RNA molecules identified by a new in vitro selection method....

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Veröffentlicht in:Biological chemistry 2005-02, Vol.386 (2), p.183-190
Hauptverfasser: Romero-López, Cristina, Barroso-delJesus, Alicia, Puerta-Fernández, Elena, Berzal-Herranz, Alfredo
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Sprache:eng
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